Protein Alignment CG5592 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_062142.1
• Gene: Slc22a5 / 29726
• RGDID: 3702
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 268/547 - (48%)
• Gaps: 31/547 - (5%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFL-FAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNR 72
            |:....|:|::|||| ||:|:::.|:.: ..|.....:|:...|: |.|.|.....| .|..:|.
  Rat     4 YDEVTAFLGEWGPFQ-RLIFFLLSASIIPNGFNGMSIVFLAGTPE-HRCLVPHTVNL-SSAWRNH 65

  Fly    73 GIP-KKQDGSF--ENCFMYNVPYDSNATN---------DANQTRSPIPCNNGWIYDRKEVPYESI 125
            .|| :.:||..  ::|..|.:...:|.:.         |..|.... .|.:||.|: |:|...:|
  Rat    66 SIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGRDVDLEQLEQE-NCLDGWEYN-KDVFLSTI 128

  Fly   126 ATEYNWVCDKRDF-GTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD 189
            .||::.|| |.|: ...:..::|||.::|....|.::|..||...|||..........:.:...:
  Rat   129 VTEWDLVC-KDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVN 192

  Fly   190 FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWR 254
            |..|.....:.|:.....:|..::|..|.:....|.:...|.:..|:..|..:||..||.|.:||
  Rat   193 FEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWR 257

  Fly   255 HYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYEL 319
            ...:.:.:|.|.........||||.||:|.|:|.....::::|||.||.:....::...    ||
  Rat   258 MLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPS----EL 318

  Fly   320 KFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVE 384
            :..|.:..:.:...||.:|....::..:.|:.|:|:::.|.........|..||::...|.:.||
  Rat   319 QDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVE 383

  Fly   385 IPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGH-WNASTAAI-AARFFATMAYNVGQQ 447
            :||.::..|||..:.|:..:||.:.|..:..||:.::... :..|||.: ..:|..|.||::...
  Rat   384 VPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSELFYLSTALVMVGKFGITSAYSMVYV 448

  Fly   448 WASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETK 512
            :.:|:.|||:|..|:.:.:...::|::|||..:....|.|.||..::..::::.|::.||.||:.
  Rat   449 YTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESF 513

  Fly   513 GATMPQTLDE-----AEKRWTLRCRDR 534
            ||.:|.|:|:     ..|:|.::.:.|
  Rat   514 GAPLPDTIDQMLRVKGIKQWQIQSQTR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	106/398 (27%)
Slc22a5	NP_062142.1	2A0119	12..520	CDD:273328	140/517 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	537..557		1/4 (25%)