Protein Alignment CG5592 and Slc22a20

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001381833.1
• Gene: Slc22a20 / 293686
• RGDID: 1311460
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 139/549 - (25%)
• Similarity: 242/549 - (44%)
• Gaps: 57/549 - (10%)

  Fly     9 YENFLLFIGDFGPFQKRLLF---WMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQK 70
            :.:.|..:|..|.||  |::   .::|...|...|:. |.|....|.:| |  :......|:...
  Rat     3 FTDLLDALGGVGRFQ--LVYTALLLLPCGLLACHTFL-QNFTAAAPPHH-C--QHPANYTEATTN 61

  Fly    71 NRG------IPKKQDGSFENCFMYNVP----YDSNATNDANQTRSPIPCNNGWIYDRKEVPYESI 125
            :.|      ||..|.|..|.|..|..|    .:.|.::....|..   |.:||:|||...| .:|
  Rat    62 DSGAWLRATIPLNQHGVPEPCQRYTEPQWALLEPNTSSHGVATEG---CKDGWVYDRSIFP-STI 122

  Fly   126 ATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDF 190
            ..|::.||:.|.....:..:|..|.:||...||.:.|..||...|..:.....:.|.|:.....|
  Rat   123 VMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGSF 187

  Fly   191 PCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRH 255
            ..:...||:.|::.:...:....|.:|.:..:.||:.| :.|.|.||||..:|..:||:|..||.
  Rat   188 SAYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAG-ILLGFSFTLGQLILAGVAYLIRPWRW 251

  Fly   256 YAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG-KIISEEVWSEMRECY-E 318
            ....|:.|.:...|.|...|||..||:..||..:.::.:::.|..|| |...|.:..|:...| :
  Rat   252 LQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTIEVVSSYIQ 316

  Fly   319 LKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLV 383
            .:||:.:...  :.||||:|.....|...|::.|.:.::||......::.....|::..:|..::
  Rat   317 NEFASVRTSN--SILDLFRTPGIRKVTCCLMMVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGII 379

  Fly   384 EIPAGIVPMLLLDRIGRKPMMSAVMLLC---AASSLFV------------GILKGHWNASTAAIA 433
            :|||.:|....:..:||:..:|:.::|.   ..:::||            .:.||       .:|
  Rat   380 DIPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQTLRTVQAALGKG-------CLA 437

  Fly   434 ARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVS 498
            :.|.....:      ..|:.||.:|..|:...::..::|.|.:||:.:.......||.......|
  Rat   438 SSFICVYLF------TGELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVLPPVSFGATS 496

  Fly   499 VI-GALIILFLPETKGATMPQTLDEAEKR 526
            |: |..:|.||.||:...:.:|:...|.|
  Rat   497 VLAGMAVICFLTETRNVPLVETIAAMESR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	105/413 (25%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	108/424 (25%)