Protein Alignment CG5592 and Slc22a26

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_017173677.1
• Gene: Slc22a26 / 236149
• MGIID: 2385316
• Length: 553
• Species: Mus musculus
• Alignment Length: 579
• Identity: 152/579 - (26%)
• Similarity: 258/579 - (44%)
• Gaps: 82/579 - (14%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKN-------HWCRVRELEGLPE 66
            :::.|..:|..|.||      ::..|||..........:||  :|       |.|.|..::. ..
Mouse     3 FQDLLNLVGSHGRFQ------ILQMAFLLICNVITMPHVIL--ENFTAANLGHRCWVHIIDN-DT 58

  Fly    67 SEQKNRGIPKKQDGSFENCFMYNVPYDSNATND-------------------ANQTRSPI-PCNN 111
            :...|.||..:.|     ....::|.|||...:                   :|.|.... ||.:
Mouse    59 NSNNNSGILSQDD-----LLRISIPLDSNLRPEKCRRFVQPQWHLLQFNGSFSNMTEPDTEPCMD 118

  Fly   112 GWIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSC 176
            ||:||::.. ..:..||:|.||..::..:.:..::.:|.:.|....|.::|..|| ..||   .|
Mouse   119 GWVYDQRTF-LSTTVTEWNLVCGSQELNSVAKFIFLIGVLAGHFVGGHLSDKFGR-KLLF---RC 178

  Fly   177 SM----IGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPI----YILTLENVGIKYRTLVGNLALT 233
            ::    |.|..:.:...|..:...||:.||    |.:||    .:|.||....|.:.||..|:::
Mouse   179 ALLQMAITGTCTALAPTFFIYCLLRFLTGL----CIIPINTNSVLLMLEWTSPKTQALVTTLSMS 239

  Fly   234 FFFTLGACLLPWLAYVISNWRHYAMVVALPI-VFMILTSLLAPESPSWLMSVGKVDRCIEVMKEA 297
            ... .|..:|..||:...||.|..:.:::|| |.:|.||....||..||:...|..:.::.:::.
Mouse   240 SHH-FGGLILAGLAFAFQNWHHLQLAISVPIFVLLIPTSRWLTESARWLIVTNKPQKALQELRKV 303

  Fly   298 AKANGKIISEEVWSE------MRECYELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVA 356
            |..||...||:|.:.      |::...:......|...:...:|.|....|.:|..|.:: .||.
Mouse   304 ASKNGIKNSEDVLTMEVVRTIMKDEIAIPRTKPSLRDLFHMPNLRKRLCLLCLLRFLQIS-PTVG 367

  Fly   357 LAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLF-VGI 420
            :..:     ::.|..::|:|.||:|...|||..:...||:.|||:   .:.:|.|....:| :.|
Mouse   368 INMN-----LQHLKGNVFLTQSLTSAFSIPATALGGFLLNYIGRR---ISQLLPCLLFGIFLLSI 424

  Fly   421 LKGHWNASTAAIA----ARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLS 481
            :.......|..:.    |...:.|.||....::||::|||:|...|.:|.|.|.:||.||||::.
Mouse   425 VSVPQEMQTLLVVLITLAGGSSAMIYNSNVLYSSELMPTVIRATALGVIGICGGVGAALSPLIMI 489

  Fly   482 THRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKRWTLRCRDRKINEDL 540
            ...|...||..|..::|::|.|:.|.|||||...:|.::.:.|..|  ....:|..||:
Mouse   490 LTLYSASLPWIIYGVLSILGGLLPLILPETKNQPLPDSIQDVECGW--ESSKQKKEEDV 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	114/415 (27%)
Slc22a26	XP_017173677.1	MFS	109..506	CDD:475125	114/415 (27%)