Protein Alignment CG5592 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 547
• Identity: 151/547 - (27%)
• Similarity: 266/547 - (48%)
• Gaps: 31/547 - (5%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFL-FAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNR 72
            |:....|:|::|||| ||:|:::.|:.: ..|.....:|:...|: |.|.|.....| .|..:|.
Mouse     4 YDEVTAFLGEWGPFQ-RLIFFLLSASIIPNGFNGMSIVFLAGTPE-HRCLVPHTVNL-SSAWRNH 65

  Fly    73 GIP-KKQDGSF--ENCFMYNVPYDSNATN---------DANQTRSPIPCNNGWIYDRKEVPYESI 125
            .|| :.:||..  :.|..|.:...:|.:.         |..|.... .|.:||.|| |:|...:|
Mouse    66 SIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQE-SCLDGWEYD-KDVFLSTI 128

  Fly   126 ATEYNWVCDKRDF-GTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD 189
            .||::.|| |.|: ...:..::|||.::|....|.::|..||...|||..........:.|...:
Mouse   129 VTEWDLVC-KDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVN 192

  Fly   190 FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWR 254
            |..|.....:.|:.....:|..::|..|.:....|.:...|.:..|:..|..:||..||.|.:||
Mouse   193 FEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWR 257

  Fly   255 HYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYEL 319
            ...:.:.:|.|.........||||.||:|.|::.....::::|||.|| |::.....:..|..:|
Mouse   258 MLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKING-IVAPSTIFDPSELQDL 321

  Fly   320 KFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVE 384
            .....||...|   ||.:|....|:..:.|:.|:|:::.|.........|..||::...|.:.||
Mouse   322 NSTKPQLHHIY---DLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVE 383

  Fly   385 IPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGH-WNASTAAI-AARFFATMAYNVGQQ 447
            :||.::..|||..:.|:..:||.:.|..:..||:.::... :..|||.: ..:|..|.||::...
Mouse   384 VPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSMVYV 448

  Fly   448 WASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETK 512
            :.:|:.|||:|..|:.:.:...::|::|||..:....|.|.||..::..::::.|::.||.||:.
Mouse   449 YTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESF 513

  Fly   513 GATMPQTLDE-----AEKRWTLRCRDR 534
            |..:|.|:|:     ..|:|.::.:.|
Mouse   514 GVPLPDTIDQMLRVKGIKQWQIQSQTR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	111/398 (28%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	144/517 (28%)