Protein Alignment CG5592 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 556
• Identity: 166/556 - (29%)
• Similarity: 265/556 - (47%)
• Gaps: 47/556 - (8%)

  Fly    10 ENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCR---VRELE---GLPESE 68
            ::.|..||:|..|||:..|.:...:..|...|.|.:|:...| ||.||   |.||.   |...:|
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTP-NHHCRSPGVAELSQRCGWSPAE 68

  Fly    69 QKNRGIP---KKQDGSF-ENCFMYNVPYDSNATN--------DANQTRSPI-PCNNGWIYDRKEV 120
            :.|..:|   ...:.|| ..|..|.|.::.:..:        .||::..|: ||.:||:||   .
Mouse    69 ELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYD---T 130

  Fly   121 PYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSV 185
            |..||.||:|.||...........:..||..:|.:..|::.|..||...|.:....:.|.|.:..
Mouse   131 PGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMA 195

  Fly   186 VCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVI 250
            :..::......||:.||.....::..|||..|.||:.||..|| :.....||:|..:|..:||.:
Mouse   196 ISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVG-ICYQIAFTVGLLILAGVAYAL 259

  Fly   251 SNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRE 315
            .|||.....|.||....:|.....||||.||:|..|..:.::::|..||.|||.:...:.|
Mouse   260 PNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQS---- 320

  Fly   316 CYELKFANEQLGKQY--TSLDLFKTFPRLVVLT-ILIVTWMTVALAYDAHVRVVEILDTDIFITF 377
                ..|:|..|.:.  :.|||.:| |::...| ||:..|.|.::.|...:..:.:...:|::.|
Mouse   321 ----LTADEDTGMKLNPSFLDLVRT-PQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDF 380

  Fly   378 SLSSLVEIPAGIVPMLLLDRIGRK-PMMSAVML---LCAASSLFVGILKGHWNASTAAIAARFFA 438
            ..|:|||.||..:.:|.:|||||: |...:.|:   .|.||......|:  |...|.|...|...
Mouse   381 FYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQ--WLKITVACLGRMGI 443

  Fly   439 TMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSP-LVLSTHRYYRPLPMFIITLVSVIGA 502
            |:||.:.....:|:.||.:|...:.:.:.|..:|.:::| ||......:...|:.:..:|.::..
Mouse   444 TIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAG 508

  Fly   503 LIILFLPETKGATMPQTLDEAEKRWTLRCRDRKINE 538
            .::|.||||||..:|:|:::|||..    |.||..|
Mouse   509 GLVLLLPETKGKALPETIEDAEKMQ----RPRKKKE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	156/528 (30%)
		MFS	141..509	CDD:119392	105/375 (28%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	156/528 (30%)
		MFS	125..492	CDD:119392	114/381 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843836
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850