Protein Alignment CG5592 and Slc22a8

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001158106.1
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 545
• Identity: 143/545 - (26%)
• Similarity: 228/545 - (41%)
• Gaps: 61/545 - (11%)

  Fly    16 IGDFGPFQKRLLFWMMPAAFLFAFTYFG-------QIFMILLPKNHWCRVRELEGLPESEQKNRG 73
            :|..||||       .....|.|....|       |||....|.:| ||..     |.:..:...
Mouse    10 VGSMGPFQ-------YLHVTLLALPILGIANHNLLQIFTATTPDHH-CRPP-----PNASLEPWV 61

  Fly    74 IPKKQDGSFENCFMY-NVPYDS--NATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDK 135
            :|...:|..|.|..: ::|..|  |.|..|.:     ||.:||||:...   ::|.||::.||..
Mouse    62 LPLGPNGKPEKCLRFVHLPNASLPNDTQGATE-----PCLDGWIYNSTR---DTIVTEWDLVCGS 118

  Fly   136 RDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVA 200
            ......:..|:..|.:||...||.::|..||.|.|..:.......|..:........:...||:.
Mouse   119 NKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLC 183

  Fly   201 GLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIV 265
            |.|::...:...||.:|.|....|. :.:..:.:.:|:|..:||.|||.:..||...:.|:....
Mouse   184 GCSISGISLSTIILNVEWVPTSTRA-ISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFF 247

  Fly   266 FMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQLGKQY 330
            ...|.|...|||..||:..||..:.::.::..|..|||  .||  .|.....||||   .|.|..
Mouse   248 IFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGK--KEE--GEKLTVEELKF---NLQKDI 305

  Fly   331 TSL-------DLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAG 388
            ||.       |||:......|...|.:.|.....||.:....||....:|:|...:...|:|||.
Mouse   306 TSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAK 370

  Fly   389 IVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIA--------ARFFATMAYNVG 445
            .:.:|.:..:||:.....:::|...:.|.:..:.........|:|        ..|.....|
Mouse   371 FITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKGCLSGSFSCLFLY--- 432

  Fly   446 QQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPE 510
               .||:.|||||..|:.|.||..::|::::|||..|......:|..|...::::|.....||.|
Mouse   433 ---TSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLE 494

  Fly   511 TKGATMPQTLDEAEKRWTLRCRDRK 535
            |....:|:|:::.:. |..:.:..|
Mouse   495 TLNRPLPETIEDIQD-WYQQTKKTK 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	140/526 (27%)
		MFS	141..509	CDD:119392	100/382 (26%)
Slc22a8	NP_001158106.1	2A0119	11..503	CDD:273328	140/526 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844029
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950