Protein Alignment CG5592 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 146/577 - (25%)
• Similarity: 260/577 - (45%)
• Gaps: 78/577 - (13%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTY------FGQIFMILLPKNHWCRVRELEGLPES 67
            :::.|..:|..|.||      ::...|:..|..      ..:.|..::| ||.|.|..|:....|
  Rat     3 FQDLLNQVGSLGRFQ------ILQMTFILIFNIIISPHSLLENFTAVIP-NHRCWVPILDNDTVS 60

  Fly    68 EQKNRGIPKKQDGSFENCFMYNVPYDSNATND--------------ANQTRSPI------PCNNG 112
            ...|..:      |.::....::|.||:...:              .|.|.|.:      ||.:|
  Rat    61 GNDNGNL------SQDDLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEPDTEPCVDG 119

  Fly   113 WIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCS 177
            |:||:... ..:|.||::.||:.:...:.:..::..|.:||.:.:|.:||..||...|.    |:
  Rat   120 WVYDQSTF-LSTIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILI----CA 179

  Fly   178 MIGGCVSVVCKDF-PCF---AASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTL 238
            .:...|:..|..| |.|   .:.||:||:|.:.......:|.:|....|::.|...|.|. ...:
  Rat   180 SLQMAVTETCAAFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLC-AGAI 243

  Fly   239 GACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGK 303
            |..:|..||:.:.||.|..:.:::||.|:::.:....||..||:...|:.:.::.:.:.|..||.
  Rat   244 GQTVLAGLAFTVRNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGM 308

  Fly   304 ------IISEEVWSEMRECYELKFANEQLGKQYTSLDLFKTFP----RLVVLTIL-IVTWMTV-- 355
                  :..|.|.:.|:|..|.......|      .|||:| |    |:.:|::: .|.|::|
  Rat   309 KNSTDVLTIEVVRTIMKEELEASQTKSSL------WDLFRT-PNLRKRICLLSLVRFVVWLSVIG 366

  Fly   356 ALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGI 420
            .|....|:|:      ::|:...|..::.|||.:|.:.|::.:||:.....::.|...|.|.:..
  Rat   367 LLINFQHLRI------NVFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLFGISILAIIF 425

  Fly   421 LKGHWNASTAAIA--ARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTH 483
            :..........:|  ...|:.::.:.....|:|:|||::|...|.:|.|.|..||.||||.:...
  Rat   426 VPQEMQILRMVLATFGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILR 490

  Fly   484 RYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKRWTLRCRDRKINEDL 540
            .|...||..|..::|.:|.|::|.|||||...:|.::.:.|.... ..|..|.|:.|
  Rat   491 TYSDSLPWIIYGVLSFLGGLVVLLLPETKNQPLPDSIQDVENEGR-ASRQGKQNDTL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	109/414 (26%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	108/415 (26%)