DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and F32H5.4

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001370023.1	Gene:	F32H5.4 / 185216	WormBaseID:	WBGene00009350	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	566	Identity:	130/566 - (22%)
Similarity:	235/566 - (41%)	Gaps:	111/566 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPPRDCEKYENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMI---LLPKNHWCRVRELE 62
            :||::.:..:||:    ..|.:...:||:   :.|:........::|:   ..||...|     |
Worm    20 LPPKEEKTLDNFM----KLGKYCWLILFF---SEFMLLSGAGNTLYMMYAGAYPKLVSC-----E 72

  Fly    63 GLPESEQKNRGIPKKQDGSFENCFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIAT 127
            | |:...|:  |.|   .||:   .:|.|   |.|..:.             ||     :.||..
Worm    73 G-PDVFIKD--ICK---SSFD---FHNPP---NCTITSK-------------YD-----FYSINV 107

  Fly   128 EYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPAL----FLANSCSMIGGCVSVVCK 188
            :|...|.:..:...|:.|..||.::|.:..|.:.|..|||..|    |:.:|.|::    :...|
Worm   108 DYGHFCGEGAWVKTSISVQMVGVLIGSVTSGAVADRYGRLKVLSVCFFMVSSLSIL----NTFAK 168

  Fly   189 DFPCFAASR-----FVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAY 248
            |...|...|     |..||...|     .:..:|:|..::|..:   |....:.....:|.::||
Worm   169 DLIYFTIIRTILSIFKGGLLSTY-----GVYKMEHVPRQHRFWI---ATMISWAPNYMILSFVAY 225

  Fly   249 VISNWRHYAMVV---ALP--IVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEE 308
            :..:|..|...:   ::|  :||     |...|||.||:..|:::...:|:|...:.:|. .|:.
Worm   226 LCHDWITYQYAIFALSMPGAVVF-----LFVKESPRWLIQAGRIEEARQVLKHIMEVDGN-TSDH 284

  Fly   309 VWSEMRECYEL-KFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWM---TVALAYDAHVRVVEIL 369
            .|:|:.|..:. |...|:..|:..:.|....|....:.::.::.|:   :.:......|..:|.|
Worm   285 SWNEIEEMLQTEKKRQEERIKKRKNYDFRHLFWNKYMASVTMILWLGMFSTSFTNYGFVFNIEKL 349

  Fly   370 DTDIFITF----SLSSLVEIPAGIVPMLLLDRIGRK--PMMSAVMLLCAASSLFVG--------- 419
            ...::|..    ||..::.|..|:.. |...::|||  .::|.:.:.....|:||.
Worm   350 SGSLYINALLMGSLRWVLNIFFGLAD-LKFAKLGRKHIHLISKLTITICVFSIFVTYYFEYEEDY 413

  Fly   420 --ILKGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSP--LVL 480
              |::      .|.:.|...|:..:........|..|||:|...::..:...::|.:|.|  .:|
Worm   414 SLIIR------VATLLASATASQVFITKSMVLMEFYPTVIRNSAVSFKSSASRIGTILGPQLFIL 472

  Fly   481 STHRYYRPLPMFIITLVSVIGALII-LFLPETKGATMPQTLDEAEK 525
            ..   |:.||..|:|...:..|:.. |.||||||..:|:|:.|..|
Worm   473 CP---YKSLPYAILTGFCLFDAIAFQLRLPETKGKPLPETMPERHK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	123/542 (23%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	90/405 (22%)
F32H5.4	NP_001370023.1	2A0119	<104..509	CDD:273328	101/432 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010