DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and C44C10.3

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_509958.2	Gene:	C44C10.3 / 183452	WormBaseID:	WBGene00008084	Length:	474	Species:	Caenorhabditis elegans

Alignment Length:	487	Identity:	115/487 - (23%)
Similarity:	205/487 - (42%)	Gaps:	94/487 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 NCFMYNVPY----DSNATNDANQTRSPIPCNNGWIYDRKEVP-YESIATEYNWVC-DKRDFGTYS 142
            |.|..:||.    |...|.|....:| .|.:|....|    | :.|:|.:::||| ....:.::.
Worm    29 NIFSIHVPKWKCGDGPVTKDCKVYQS-CPKDNLTFVD----PIFTSVAMDFDWVCGSSAHYQSFF 88

  Fly   143 VVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYC 207
            .:|.::|.:||.:.||.::|..||.|...|....::|....:.:..:......:||.:|||:...
Worm    89 SLVQYLGVLVGTVLFGTLSDKYGRKPIGILVIVIAIISLLGTGLSPNRQLLFIARFCSGLSIAGV 153

  Fly   208 FVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPW-------LAYVISNWRHYAMVVA---L 262
            .|.|....||:: :.::.:|    :..||..|     |       :.|:...||..:.|.|   :
Worm   154 LVCICAWILESI-LSHQRMV----IRAFFNWG-----WTRVFITVVCYLTQEWRLASYVCAACLV 208

  Fly   263 PIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG--------KIISEEVWSEMRECYEL 319
            |.:.|::  .|.|||..||.|.|:..:.||..|..||..|        |:|..:
Worm   209 PALLMLI--FLIPESAIWLHSKGETAKMIESEKFMAKIAGVSYVPIEHKLIHSK----------- 260

  Fly   320 KFANEQLGKQYTSLDLFKT---FPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSS 381
                       |.|:...|   |.:|.||.|:   |..||:...|:......|..::::..:|..
Worm   261 -----------TLLETLNTKGLFKKLFVLWIM---WFFVAVCGFANDLNSNSLAGNLYLNQALFG 311

  Fly   382 LVEIPAGIVPMLLLD--------RIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIAARFFA 438
            ::.:.:.|| :|.:|        |...:...|.:::.....::|:.| ..|   .|..:....|.
Worm   312 ILLVLSKIV-LLFVDTKFENFKRRTLHQGSQSGMIISFLILAIFLWI-DYH---GTGFLIVYLFG 371

  Fly   439 TMAYNVGQQW------ASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLV 497
            ||.  :...|      |.|.:.|..|...:...::|.::|:||:|.:...:.::.|...|.|.::
Worm   372 TMF--IEYTWDAVYLCAIESMETSSRASAVGSCSLMARIGSLLAPFLTYANTWWPPAVYFTIIVL 434

  Fly   498 SVIGALI-ILFLPETKGATMPQTL---DEAEK 525
            ..:..:| .:||.|||...:.:..   |||::
Worm   435 GTVNLIISFMFLQETKNVNLDEVQVNDDEAQE 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	112/476 (24%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	91/403 (23%)
C44C10.3	NP_509958.2	2A0119	<64..456	CDD:273328	102/439 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910