DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and pes-23

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_509167.2	Gene:	pes-23 / 180963	WormBaseID:	WBGene00003987	Length:	520	Species:	Caenorhabditis elegans

Alignment Length:	478	Identity:	102/478 - (21%)
Similarity:	181/478 - (37%)	Gaps:	108/478 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 NNGWIYDRKEVPYESIATEYNWVCDKRDFGTY----SVVVYFVGCIVGCLCFGFITDHSGRLP-- 168
            ||...|          :|...|:.|..:....    .:.:..||..||.:.||:|:||.||..
Worm    58 NNSNFY----------STHAQWITDDTNVSVLWWENVIAIQQVGIFVGSILFGYISDHFGRQKVC 112

  Fly   169 --ALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLA 231
              :|.:::...::.|.:|...    ..|..||:.|.......|..:.||.|.:..:.|.|....|
Worm   113 QYSLLISSVILLVEGFLSSTI----LIALCRFIIGTQTGAIIVVSWSLTTELISPRTRFLARAFA 173

  Fly   232 LTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVF-MILTSLLAPESPSWLMSVGKVDRCIEVMK 295
               .:..|...|..:.:...|||....|.|...:| .:|.....||||::|...||......::.
Worm   174 ---NWPTGKFALALICFFSQNWRISLHVCAAFTLFGALLYIFFVPESPTYLQCHGKRTEAHNIVA 235

  Fly   296 EAAK-ANGKII-------------SEEVWSEMRECYE---LKFANEQLGKQYTSLDLFKTFPRLV 343
            :..| :|||.:             ..::|.  :|.|.   :.|.:..:...:|:..|  .|..::
Worm   236 DVFKNSNGKCVIALPGGIRSKPLTFRQIWK--KEKYRNVIILFGSIWVMTNFTATML--DFSEVI 296

  Fly   344 VL-TILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAV 407
            :. ..||::.|.:| ...|..::             |..||||..||:....|..|.   :....
Worm   297 IFHNNLILSQMLLA-GVPAICKI-------------LLGLVEIYFGIISRRNLHLIS---LCING 344

  Fly   408 MLLCAASSLFV-GILKGH------------------WNASTAAIAARFFATMAYNVGQQWASEIL 453
            :.:||:..|.: |:.|.:                  |:|....:.                 |.:
Worm   345 ISMCASGVLILFGLQKNYPTIYVLVFLIGYASIEFIWDACYLCVV-----------------EQV 392

  Fly   454 PTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALI-ILFLPETKGATMP 517
            ||.:||......:.:.::..:|:..:....:.:.|.|:||....::|..|| ..||.|:|.|.:
Worm   393 PTEVRGTISGACSFLSRLSGILASKMTIVKQRWEPAPLFIAFATAIIHFLIAFFFLNESKDANL- 456

  Fly   518 QTLDEAEKRWTLRCRDRKINEDL 540
                 .|..:|||...:|:::.:
Worm   457 -----GEIGFTLRRISQKVSQKI 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	97/455 (21%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	87/414 (21%)
pes-23	NP_509167.2	2A0119	<82..458	CDD:273328	91/426 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910