Protein Alignment CG5592 and lelo-2

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001408283.1
• Gene: lelo-2 / 175300
• WormBaseID: WBGene00022348
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 143/580 - (24%)
• Similarity: 240/580 - (41%)
• Gaps: 118/580 - (20%)

  Fly     8 KYENFLL-FIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLP----KNH---WC-------- 56
            |:::||. ::|:.|.:||.                  |.|::.||    ..|   |.
 Worm     2 KFDDFLFTYLGEMGKYQKI------------------QFFLVCLPTIVVSMHALSWTFASVDTPY 48

  Fly    57 RVRELEGLPESEQKNRGIPKKQDGSFENCFMYNVPY------DSNATNDANQT------------ 103
            |.|....|||.|                      ||      .:..||||:..
 Worm    49 RCRLPSDLPEKE----------------------PYYTTLLNFTKCTNDADANVPISEYGKPGVT 91

  Fly   104 ----RSPIPCN---NGWIYDRKEVPYESIATEYNW--VCDKRDFGTYSVVVYFVGCIVGCLCFGF 159
                |..:|.|   :..|:|..:|.|.::   ..|  .||:..........|:||.:.|...||.
 Worm    92 CHYDRCTLPDNETCHEHIFDHSKVEYTAV---QRWEITCDRSWIKATIQAAYYVGQMAGSTTFGM 153

  Fly   160 ITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYR 224
            :.|..||....|||....:....:..:...:..:|.:|...|.|....||...::.:|.||.|||
 Worm   154 LGDRIGRKKVFFLAIVIQITCAYLIAIAPYWWLYALARAGTGFSHPGIFVIAVVIGMELVGPKYR 218

  Fly   225 TLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDR 289
            .| .::....||.||...|...|...:|::...:|:|.|.:..:....|.|||..||:|..:...
 Worm   219 KL-ASVITGLFFALGQIFLGIEAIYFTNYQILHVVIASPALLFLSYWWLVPESARWLVSQKRYKE 282

  Fly   290 CIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQLG---------KQYTSLDLFKTFPRLVVL 345
            ..||:::||..||.::.|..|.::.:        ...|         |:.|..|||:| |.|...
 Worm   283 ADEVLQKAASVNGTVLPENWWEQLDD--------STTGGGGAPGAPTKKLTGADLFRT-PELRKR 338

  Fly   346 TILI-VTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVML 409
            |::: ..|..:::.|........:|..||::.|..::.|||||..:..||:|||||: ::.|..|
 Worm   339 TLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIGRR-LILAGGL 402

  Fly   410 LCAASSLFVGILKGH----WNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQ 470
            ..|.:.|.|..|.|.    |.|.|.....:...|..|.....::.|:.|||:|...:...:.:.:
 Worm   403 FIAGACLLVNWLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGFCSTIAR 467

  Fly   471 MGALLSPLVL-----STHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEK 525
            :||:.:..:.     ...:.:..:|...:.:::.:  :.:||||||.|..:|::::|.|:
 Worm   468 VGAIAASYISMWIAEQFGKVFMIIPFGCMAVLAAV--MTLLFLPETMGKPLPESIEEIEE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	107/416 (26%)
lelo-2	NP_001408283.1	MFS_SLC22	107..508	CDD:340875	106/416 (25%)