DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and B0252.3

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001021888.1	Gene:	B0252.3 / 174130	WormBaseID:	WBGene00015088	Length:	484	Species:	Caenorhabditis elegans

Alignment Length:	424	Identity:	102/424 - (24%)
Similarity:	191/424 - (45%)	Gaps:	53/424 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 IATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSM-IGGCVSVVCK 188
            :|.|::...|.......:...|.||.::|.:....:.||.|||| :|:|....| :||.:|....
Worm    79 VADEFDLTGDASWLAESTTTFYMVGNMIGGMFIPPLADHYGRLP-VFVATVLLMAVGGMISAFST 142

  Fly   189 DFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFT---------LGACLLP 244
            ....|...|.:.|:......:..::|..||..::.|          |||         :|||.|.
Worm   143 SIMMFCIMRMIHGIFYTAAGLAGWVLGYENTPLRLR----------FFTSVYFGVMWVVGACFLG 197

  Fly   245 WLAYVISNWRHYAMVVALPIVFM-ILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEE 308
            .|||::.:||:....:::|.:|: :|..:..|||..:|:|..:.::....:::.....|.|.:.:
Worm   198 LLAYILPDWRYLMFCISVPNIFVALLIYMTVPESLHFLVSSQQNEKIEAWLEKIRGPKGDISASD 262

  Fly   309 VWSEMRECYELKFANEQLGKQYTSL--DLFKTFPRLVVLTILIVT--WMTVALAYDAHVRVVEIL 369
            :..:          .::.|..:.:|  :::|  .::.::.:|::|  |:.....|.........|
Worm   263 IVED----------RDENGSSFKTLCREMWK--HKMFIVYVLVMTYIWIVDTFIYFGLAFYSTNL 315

  Fly   370 DTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKG-------HWNA 427
            ..::::.|.|.||||.||.|...:.:::.|||.::|...::...|  |:||:..       .|..
Worm   316 AGNLYLNFVLMSLVEAPAYIFSPIFMNKYGRKVLISGTHIIAGLS--FLGIVLSSEAWHIHFWLL 378

  Fly   428 STAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMF 492
            ...||:..|.:...:      ||||.||..|.:.:.....:.:.|.:|||.:......:...|..
Worm   379 GKFAISCSFMSIYMF------ASEIFPTDGRNKCIGFCETLSRFGGMLSPYLSHLTAVHALAPAI 437

  Fly   493 IITLVSVIGALIILFLPETKGATMPQTLDEAEKR 526
            .::|::|.|.|:.|.||||....:|.|:.|...|
Worm   438 TLSLIAVSGGLLTLILPETLNTKLPSTIAETASR 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	99/415 (24%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	91/389 (23%)
B0252.3	NP_001021888.1	MFS	87..454	CDD:119392	92/397 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163037
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940