DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and UST4r

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	576	Identity:	141/576 - (24%)
Similarity:	246/576 - (42%)	Gaps:	101/576 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNRG 73
            ::..|..:|..|.||...:.:::..:.:.......:.|...:| :|.|.|..|:.:..|:..:|.
  Rat     3 FQELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIP-SHRCWVPILDNVTVSDNDSRI 66

  Fly    74 IPKKQDGSFENCFMYNVPYDSNA--------------TNDANQTRSPI------PCNNGWIYDRK 118
            :  .||    .....::|.||:.              ..|.|.|.|.|      ||.:||:|||.
  Rat    67 L--NQD----KLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCVDGWVYDRS 125

  Fly   119 EVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCV 183
            .. :.:..||:|.||:.:...:.:.:.:.:|..:|.:..|.::|..||...|..|    ::...:
  Rat   126 NF-HSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYA----LLQMAI 185

  Fly   184 SVVCKDFP----CFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLV---GNLALTFFFTLGAC 241
            :..|..|.    .:.:.||:||:|:....|.|.:|..|....|:.|:|   |:.|.:|    |..
  Rat   186 TETCAGFAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSF----GGM 246

  Fly   242 LLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG---- 302
            :|..||:...||.|..:.:::||.|.::.:....||..||:.:.|..:.::.:|:.|..||
  Rat   247 ILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGMKKS 311

  Fly   303 --KIISEEVWSEMRECYELKFANEQLGKQYTSLDLFKT-----------FPRLVVLTILIVTWMT 354
              .|..|.|.:.|::  ||:.|..:...:    |||.|           |.||    :.|::.:.
  Rat   312 GDNITMEVVRTSMKK--ELEAAKMRPSPR----DLFHTPILRKQIYILSFIRL----LFILSGVG 366

  Fly   355 VALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSL--- 416
            ||:........:|:|.    |..|:||::   ..::...:|:.|||:.....:|.|...|.|
  Rat   367 VAIHLQHLSNNIELLQ----ILISVSSIL---FSVIGHFVLNHIGRRITQMVIMFLRGISILTAI 424

  Fly   417 ----------FVGILKGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQM 471
                      |:           .|:.|...|.::|......|:|:|||.||.....:|.:.|.:
  Rat   425 FAPQEMETLRFI-----------MAMMAEGLAALSYAANSLHANELLPTTLRATARGVIGMFGNI 478

  Fly   472 GALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKRW 527
            |..|:||.:....|...||.......:::...|:|.|||||...:|....:.|..|
  Rat   479 GFFLAPLCMMLASYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHDVENDW 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	138/558 (25%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	98/404 (24%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	110/443 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940