Protein Alignment CG5592 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 106/449 - (23%)
• Similarity: 195/449 - (43%)
• Gaps: 81/449 - (18%)

  Fly   109 CNNGWIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLA 173
            |.:||     :||.|.::                   :.:|.::||:..|...|..|| .|:|:|
Human    13 CGDGW-----KVPLEQVS-------------------HLLGWLLGCVILGAGCDRFGR-RAVFVA 52

  Fly   174 NSCSMIG-GCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFT 237
            :.....| |....:...||.....|.:.|.::....:.:|:..||.....:| |..::....|..
Human    53 SLVLTTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHR-LAFSMGAGLFSV 116

  Fly   238 LGACLLPWLAYVISNWRHY----AMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAA 298
            :|..|||.||.::.:||..    |::..|.::|....:|. ||||.||::.|:|.|..:::...|
Human   117 VGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALF-PESPCWLLATGQVARARKILWRFA 180

  Fly   299 KANGKIISEEVWSEMRECYELKF--ANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMT-VALAYD 360
            :|:|....:....|.....||..  |.....:.::.|.|.:|          .|||.. :.|.:.
Human   181 EASGVGPGDSSLEENSLATELTMLSARSPQPRYHSPLGLLRT----------RVTWRNGLILGFS 235

  Fly   361 AHV---------RVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPM---------MSAV 407
            :.|         |.:.......::.:.|.:.:|..|.:..:|..|..||:|:         ::::
Human   236 SLVGGGIRASFRRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASL 300

  Fly   408 MLLCAA------SSLFVGILKGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIIN 466
            :||..|      :.||:.:|....:.:.:|:::.|            |:|:.|||:||.||.::.
Human   301 LLLAGAQYLPGWTVLFLSVLGLLASRAVSALSSLF------------AAEVFPTVIRGAGLGLVL 353

  Fly   467 IMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEK 525
            ..|.:|....||.....|....|...:...::|:..|.:|.|||::...:||:|.:|::
Human   354 GAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADR 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	97/427 (23%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	96/418 (23%)