Protein Alignment CG5592 and LOC1273135

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_563311.4
• Gene: LOC1273135 / 1273135
• VectorBaseID: AGAMI1_006148
• Length: 578
• Species: Anopheles gambiae
• Alignment Length: 552
• Identity: 111/552 - (20%)
• Similarity: 196/552 - (35%)
• Gaps: 182/552 - (32%)

  Fly   107 IPCNNGWIYDRKEVPYESIATEYNWVCDKR----DFGTYSVVVYFVGCIVGCLCFGFITDHSGRL 167
            :||....:::...:.|...:.|    ||..    |.|..:.:.| .|.|.....:||::|..||.
Mosquito    56 MPCCMTTVFETTTMSYVLPSAE----CDLNLTLADKGMLNAITY-TGMITSAFLWGFLSDTYGRK 115

  Fly   168 PAL---FLANS-----CSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYR 224
            ..|   ||.:|     |::....|:::        ..:|:.|..:...|..:.....|...:::|
Mosquito   116 RLLVVGFLLDSTFNVLCALSQNMVAIM--------VFKFMGGFVICGPFAVLMAYLSEFHSLQHR 172

  Fly   225 TLVGNLALTFFFTLGACLLPWLAYV----------------ISNWRHYAMVVALPIVFMILTSLL 273
            :.| .:.|..|::....|||.||::                |.:|:.:..|..||.|...::.:.
Mosquito   173 SRV-MIVLGVFYSAANMLLPALAWLIIPQSWNLIIGDGVLEIHSWQIFLAVSCLPGVLSGISVMF 236

  Fly   274 APESPSWLMSVGKVDRCIEVMK--------------------EAAKANGKII------------- 305
            .||||.:|||.|:.:|.:.:.:                    |.:..:|.|:
Mosquito   237 LPESPKFLMSKGQNERALAIFRRLYAINTRDRQEFPIRVLVDELSPVSGPIVPASGKQASGKPTT 301

  Fly   306 -----SEEVWSEMRECYE---LKFANEQL-------GKQYTSLDLFKTF----PRLVVLTIL--- 348
                 :....|.:.|.:.   :.|....|       |.|:..|....||    |:|  .||:
Mosquito   302 QPPPAAAAAPSGLGEGFRQLGIMFRKPHLTNACLVYGIQFGILLGLNTFRLWVPQL--FTIIEEF 364

  Fly   349 ----------IVTWMTVA--LAYDAHVR----------------------VVEILDTDIFIT--- 376
                      :.:..|:.  |||..:..                      .:|.||..:..|
Mosquito   365 EHEQHLLPDGLASQATLCEMLAYKVNKTEQLQQQWLERDVSRALHGPDPVAMEPLDDVLMCTPTT 429

  Fly   377 ------FSL-SSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLC---------AASSLFVGILKGHW 425
                  :|| ...|.|.|..|..::::.||.:.:::..:||.         |.|||...||...:
Mosquito   430 EGRVYLYSLIIGCVGIGAYAVTTVMINSIGNRNILTYGLLLAGSCGTALYWARSSLVTLILSSCY 494

  Fly   426 -----NASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRY 485
                 .||||.:.|              ...:.||.:|...:::..:.|:.|:::..:|......
Mosquito   495 ITICSIASTALVGA--------------VVAMFPTSMRTMVVSLTMMFGRTGSIIGNVVFPYLMA 545

  Fly   486 YRPLPMFIITLVSVIGALIIL------FLPET 511
            ...||.|:     :|||::|.      .||.|
Mosquito   546 LGCLPPFV-----MIGAIVIAVAAVSRLLPRT 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	106/542 (20%)
LOC1273135	XP_563311.4	synapt_SV2	<35..>276	CDD:130366	50/233 (21%)
		2A0119	<70..577	CDD:273328	109/538 (20%)