Protein Alignment CG5592 and SLC22A9

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 139/580 - (23%)
• Similarity: 241/580 - (41%)
• Gaps: 109/580 - (18%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAF---TYFG---QIFMILLPKNHWCRVRELEGLPES 67
            :::.|...||...||      ::...||..|   ||..   :.|...:| .|.|.|..|:....|
Human     3 FQDLLGHAGDLWRFQ------ILQTVFLSIFAVATYLHFMLENFTAFIP-GHRCWVHILDNDTVS 60

  Fly    68 EQKNRGIPKKQDGSFENCFMYNVPYDSNA------------------------TNDANQTRSPIP 108
            :.....:  .||.    ....::|.|||.                        |:||:..    |
Human    61 DNDTGAL--SQDA----LLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADME----P 115

  Fly   109 CNNGWIYDRKEVPYES-IATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFL 172
            |.:||:|||  :.:.| |.||::.|||.:...:.:..|:..|.:||.:..|.::|..||   .|:
Human   116 CVDGWVYDR--ISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGR---RFV 175

  Fly   173 ANSC----SMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALT 233
            ...|    :::|.| :.:...|..:.:.||::|::.........:|..|....:::.:
Human   176 LRWCYLQVAIVGTC-AALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAM------- 232

  Fly   234 FFFTLGAC-------LLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCI 291
             ..|||.|       .|..||:.|.:|....:||::|...:.|||....||..||:...|.:..:
Human   233 -GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGL 296

  Fly   292 EVMKEAAKANG------KIISEEVWSEMRECYELKFANEQLGKQYTSLDLFKTFPRLVV-LTILI 349
            :.:::||..:|      .:..|.:.|.|::  ||:.|.    |:..||......|.:.. :::|.
Human   297 KELRKAAHRSGMKNARDTLTLEILKSTMKK--ELEAAQ----KKKPSLCEMLHMPNICKRISLLS 355

  Fly   350 VTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLL---C 411
            .|.....:||......|:.|..::|:..:|...|.:.|..|....|..:.|:.....:|.|   |
Human   356 FTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAIC 420

  Fly   412 AASSLFV--------GILKGHWNASTAAIAARFFA-TMAYNVGQQWASEILPTVLRGQGLAIINI 467
            ..:.:||        .:|      :|..:.|...| |:|:..|    :|::||::|.:.:.|...
Human   421 LLAIIFVPQEMQTLREVL------ATLGLGASALANTLAFAHG----NEVIPTIIRARAMGINAT 475

  Fly   468 MGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTL-DEAEKR 526
            ...:...|:||::....|..|||..|..:...|.....|.||||:...:..|: ||..:|
Human   476 FANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNER 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	102/426 (24%)
SLC22A9	NP_543142.2	MFS_OAT	109..517	CDD:340932	107/441 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		3/8 (38%)