Protein Alignment CG5592 and Slc22a7

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_659105.2
• Gene: Slc22a7 / 108114
• MGIID: 1859559
• Length: 540
• Species: Mus musculus
• Alignment Length: 550
• Identity: 158/550 - (28%)
• Similarity: 267/550 - (48%)
• Gaps: 40/550 - (7%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQK--- 70
            :|..|..:|.|||||.|.|..:....||....:...|||..:|.:| |      .||::...
Mouse     3 FEELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHH-C------ALPDAPANLSH 60

  Fly    71 -----NRGIPKKQDGSFENC--FMY-----NVPYDSNATNDANQTRSP--IPCNNGWIYDRKEVP 121
                 ...:|::.||||.:|  |.|     ||...:...|.......|  :||:.||.|||.|..
Mouse    61 QDLWLKTHLPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFS 125

  Fly   122 YESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVV 186
             .:||||::.||.:|.....:...:|:|.::|.:.:|:::|..||...|.:|...::..|.:|..
Mouse   126 -STIATEWDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAA 189

  Fly   187 CKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVIS 251
            ..::..|..:|.:.|.::....:.:..|.||.:.:::||:.|.::.| |:|.|..||..:.|:|.
Mouse   190 SVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTT-FWTGGVLLLTLVGYLIR 253

  Fly   252 NWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMREC 316
            :||...:...||.|..|::....|||..||::.|:|:...:.:...||.||:.|||:..|:  |.
Mouse   254 SWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQ--EA 316

  Fly   317 YELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSS 381
            .......|::.::.:.||||:|.....|....::.|..|..:|.........|...::.|..|..
Mouse   317 LNKVITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFG 381

  Fly   382 LVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKG----HWNASTAAIAARFFATMAY 442
            .||:|:.|....|:..:||: :..|.|||..|.:..:.:|..    .| .:...:..:.|:..|:
Mouse   382 AVEVPSKITVFFLVRLVGRR-LTEAGMLLATALTFGISLLVSSDTKSW-ITALVVIGKAFSEAAF 444

  Fly   443 NVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILF 507
            .....:.||:.|||||..|:....::|::||.|:|||:.....:..||......:|.:.|..:|.
Mouse   445 TTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLL 509

  Fly   508 LPETKGATMPQTLDEAEKRWTLRCRDRKIN 537
            |||||.|.:|:|:.:.|:      :.|||:
Mouse   510 LPETKKAQLPETIQDVER------KGRKID 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	111/399 (28%)
Slc22a7	NP_659105.2	2A0119	11..521	CDD:273328	151/522 (29%)