Protein Alignment CG5592 and sv2b

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 573
• Identity: 102/573 - (17%)
• Similarity: 186/573 - (32%)
• Gaps: 215/573 - (37%)

  Fly   126 ATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDF 190
            :.|.:....:.:.|...::|| :|.::|...:|.:.|..||...|.::.:.:.....||...:.:
 Frog   163 SAEKDMCLSRSNKGMLGLIVY-LGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGY 226

  Fly   191 PCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLA-LTFFFTLGA--------CLLP-- 244
            ..|...|.::|..:......::....|.:..:.|.  .:|: |..|:.:||        .::|
 Frog   227 GLFLFCRLISGFGIGGSLPIVFAYFSEFLAREKRG--EHLSWLCMFWMIGAVYAAAMAWSIIPHY 289

  Fly   245 -W-----LAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEA----AK 299
             |     ..|...:||.:.::..||.:..|:.....||||.:|:..||.|....::|..    .:
 Frog   290 GWGFSMGTHYHFHSWRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMR 354

  Fly   300 ANGK--------------------------------------IISEEVWSEMRECYELKFANEQL 326
            |.|:                                      .:.:::|..|..|:..:|....:
 Frog   355 AKGEPEKVFTVSHIKTPKQPDEFIEIQSSTGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTI 419

  Fly   327 GKQYTSLDLFKTFPRLVVLTILIVTWMTVALAY---------------------------DAHVR 364
                                .|.|.|.|::|:|                           |.:|:
 Frog   420 --------------------FLAVVWFTMSLSYYGLTVWFPDTIRYLQDEDYASKVKRFTDENVK 464

  Fly   365 ---------------------------------------------------VVE--------ILD 370
                                                               :.|        ..:
 Frog   465 NFNFNFTLENQIHEDGEYYNDRFYKMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYN 529

  Fly   371 TDIF-----------ITFS-----------------------LSSLVEIPAGIVPMLLLDRIGRK 401
            ||::           :|||                       |.||..:|..|:..||:|:|||.
 Frog   530 TDLYQHKFIDCNFINVTFSQPKEGCHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRI 594

  Fly   402 PMMSAVMLLCAASS--LFVGILKGHWNASTAAIA--ARFFAT--MAYNVGQQWASEILPTVLRGQ 460
            .|::..||:.|...  ||.|      |:.:|.|.  ..|..|  .|:|.......|:.||..|..
 Frog   595 RMIAGSMLISAVCCFFLFFG------NSESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRAT 653

  Fly   461 GLAIINIMGQMGALLSPLVLSTH-RYYRPLPMFIITLVSVIGALIILFLPETK 512
            ...|:|.:.::.|:....:.::. ...:.:|:.:.:...|.|.||.|.||||:
 Frog   654 AFGILNGLCKLAAIFGNSIFASFVGITKVIPILLASTALVGGGLISLRLPETR 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	98/568 (17%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	102/573 (18%)