Protein Alignment CG5592 and slc22a23

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_002936473.1
• Gene: slc22a23 / 100491610
• XenbaseID: XB-GENE-966989
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 582
• Identity: 130/582 - (22%)
• Similarity: 241/582 - (41%)
• Gaps: 95/582 - (16%)

  Fly     3 PRDCEKYENFLL--------FIGDFGPFQKR--LLFWMMPAAFLFAFTYFGQIFMILLPKNHWCR 57
            |..|.:|.:.||        |:|..|.:.||  ||.| :||.|| :|:.|...|::..| :.||:
 Frog    45 PEHCSRYNSLLLDYDGSVLPFLGGLGSYNKRLVLLTW-IPALFL-SFSQFSDFFLLDQP-DKWCQ 106

  Fly    58 VRELEGLPESEQKNRGIPKKQDGSFENCFMY---NVPYDSNATNDANQTRSPIPCNNGWIYDRKE 119
            |....|   .....|.:....:.|.....:.   .:|.....|:..|.|.|.: |.. |.|..:.
 Frog   107 VNSSGG---EHGPGRVVSHVGNDSSGGLLLLPPPQLPTTPTPTSATNYTDSCL-CTK-WDYRIRA 166

  Fly   120 VPYESIATEYNWVCD---KRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGG 181
            ...:::.::::.|||   |.....:|::   ||.|.|.|..|.:.|..||...|.::...::|.|
 Frog   167 GLVQNVVSKWDLVCDSSWKVHIAKFSLL---VGMIFGYLITGCVADWIGRRLVLLISVIFNLIFG 228

  Fly   182 CVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWL 246
            ....:..|...|:..||..|..:....:.:|.|.:|.....:|.:: .:..:|....|..|||.:
 Frog   229 LTVALSVDVNMFSTLRFFEGFCLAGIILSLYALRIELCPPGHRFMI-TMVASFIGMAGQFLLPGI 292

  Fly   247 AYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWS 311
            |.:..:|:....|:..|.:.|:...::.|||..|||:..:.|...:.:.:....|...:..:|..
 Frog   293 AALCRDWQVLQAVIICPFILMLFYWVIFPESLRWLMATMQFDASKKQILKMIHRNRVNMESDVKG 357

  Fly   312 EM----RECYELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVT---WMTVAL-------AYDA- 361
            .|    ||.|                    |.|:.|.:..::.|   |..:.:       .|..
 Frog   358 VMPELEREVY--------------------TRPKKVCIVKVVGTRNLWKNILVLCVNSLTGYGIH 402

  Fly   362 HVRVVEILDTDI--------FITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLF- 417
            |.....::|.::        ::.:...:.:.:.:.:....::..:||:..:...|:|.|.:||.
 Frog   403 HCFAKSLMDPELNTSFMHNFYVNYFAMAGITLASCLAMCPVVGFLGRRGGLLLFMILTALASLLQ 467

  Fly   418 VGILK--GHWN---------------ASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAII 465
            :|:|.  |.::               :...:|...|.:....::...:.:||.|||:||.||.::
 Frog   468 LGLLNLIGKYSQRPETGLSDIVKNKFSIIFSIIGMFSSHAVGSLSVFFCAEITPTVIRGGGLGLV 532

  Fly   466 NIMGQMGALLSPLVLSTHR---YYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAE 524
            ......|:|.:| ::..|.   |:  |...|....::|..:.||.|||:|...:|:.:.|.|
 Frog   533 LASAGFGSLTAP-IMELHNQKGYF--LHHIIFACCTLICIICILLLPESKNQNLPENIPEGE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	90/442 (20%)
slc22a23	XP_002936473.1	MFS_SLC22A23	149..562	CDD:341002	91/441 (21%)