DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and slc22a13

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	530	Identity:	149/530 - (28%)
Similarity:	253/530 - (47%)	Gaps:	33/530 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVREL----EGLPESEQ 69
            :...|..:|:||.|||:|:..:...:||.||..|.|:|| .:|..|.|..|.:    ..|.|:|:
Frog     4 FAEILKNVGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFM-EIPVPHRCDSRWILLINPNLTEAER 67

  Fly    70 KNRGIPKKQDGSFENCFMYN-VPYDSNATN--DANQTRSPIPCNNGWIYDRKEVPYESIATEYNW 131
            .|..||:...|.:|.|.||: |.:|..:..  ..|.|.   ||.:||.||..| ...::.|:::.
Frog    68 LNYTIPRDGRGQYEQCLMYSPVQWDMESIEKFGLNSTG---PCQDGWEYDTSE-QKSTLVTQFDL 128

  Fly   132 VCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAAS 196
            ||.:|:....|..||..|.::|.|.||.:.|..||.|.:.|:....::.|..:.....|..:.|.
Frog   129 VCHRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHFYVYTAF 193

  Fly   197 RFVAGLSMNYCFVPIYILTLENVGIKYR---TLVGNLALTFFFTLGACLLPWLAYVISNWRHYAM 258
            |:|.|.||:...:...:|..|.||...|   |:..::.    |.:|...|..::|.|.|||...:
Frog   194 RWVVGTSMSGLMINNLVLGAEWVGSSRRACATITAHVC----FAVGLMALAGVSYGIRNWRLLQI 254

  Fly   259 VVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFAN 323
            |.:.|...:.....:.|||..||::.||.::.::::|:||..|.|.|.|::.        .:|..
Frog   255 VSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLL--------FQFNE 311

  Fly   324 EQLGKQYTSLDLF--KTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIP 386
            |:..|....:|||  ||..:|.::..|:  |...:|.|......|.....||::|..:...||||
Frog   312 EKSPKSGNMIDLFRNKTLRKLTLVMCLV--WFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAVEIP 374

  Fly   387 AGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTA--AIAARFFATMAYNVGQQWA 449
            |.|..|..:...||||.....:.|.....|.:..:..:...:..  |:..:|....::::...:|
Frog   375 ARIGAMFAVQLFGRKPSQMFCLFLGGTVCLIITAIPRNLPIAITILAVIGKFSIASSFSICYIYA 439

  Fly   450 SEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGA 514
            :|:.|||:|..|:.:.::..::..:.:||:....:|:..:||.|.....:||.::...||||:..
Frog   440 AEVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETRNK 504

  Fly   515 TMPQTLDEAE 524
            .:.....:.|
Frog   505 DLQDHTQQDE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	147/515 (29%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	98/374 (26%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	147/515 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I9954
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920