Protein Alignment CG5592 and sv2a

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 572
• Identity: 100/572 - (17%)
• Similarity: 182/572 - (31%)
• Gaps: 229/572 - (40%)

  Fly   139 GTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLS 203
            |...::|| :|.:||...:|.:.|..||...|.::.|.:.:....|...:.:..|...|.::|:.
 Frog   192 GMLGLIVY-LGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVG 255

  Fly   204 MNYCFVPIY------ILTLENVGIKYRTLVGNLA-LTFFFTLG---ACLLPWL------------ 246
            :... :||.      .|..|..|       .:|: |..|:.:|   |..:.|.
 Frog   256 IGGS-IPIVFSYFSEFLAQEKRG-------EHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFQMG 312

  Fly   247 -AYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKI------ 304
             ||...:||.:.:|.|.|.||.|......||||.:.:..||.|....|:|:....|.:.
 Frog   313 SAYQFHSWRVFVLVCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPER 377

  Fly   305 ------------------------------------ISEEVWSEMRECYELKFANEQLGKQYTSL 333
                                                :|:|||:...:|:         ..:|..:
 Frog   378 VFSVTQIKTIKQDDELVEIQSDTGALHRRWMIKLLNLSQEVWANFHQCF---------APEYRRI 433

  Fly   334 DLFKTFPRLVVLTILIVTWMTVALAYDA----------HVRVVE--------------------- 367
            .|           :::..|.|::.:|..          |::.::
 Frog   434 TL-----------MMMAVWFTMSFSYYGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFT 487

  Fly   368 -------------------------------------------------------ILDTDIF--- 374
                                                                   ..:||:|
 Frog   488 LENQVHRKGEYHNDKFIGLKLKSVIFEDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYK 552

  Fly   375 -------------------ITFS--------------LSSLVEIPAGIVPMLLLDRIGRKPMM-- 404
                               :.||              |.:|..:|..||..||:|:|||..|:
 Frog   553 FINSKFTNSTFLHSKEGCQLDFSDDINNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAG 617

  Fly   405 SAVMLLCAASSLFVGILKGHWNASTAAIAARFF----ATMAYNVGQQWASEILPTVLRGQGLAII 465
            |:||...:...||.|      |:.:|.||....    :..::|.......|:.|:..|......:
 Frog   618 SSVMSCISCFFLFFG------NSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFL 676

  Fly   466 NIMGQMGALLSPLVLSTH-RYYRPLPMFIITLVSVIGALIILFLPETKGATM 516
            |.:.::.|:|...:.::. ...:.:|:.:.:....:|:.:.|.||||:|..:
 Frog   677 NALCKLAAVLGISIFTSFVGVAKAVPILLASAALAVGSFLALKLPETRGQVL 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	95/563 (17%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	100/572 (17%)