DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	558	Identity:	147/558 - (26%)
Similarity:	254/558 - (45%)	Gaps:	67/558 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCR----VRELEGLPESEQKNRGIPK 76
            |||||.|||.|||.:.....:..|.....:|. ....||.|.    ::....|.:.||.|..:|:
Zfish    11 IGDFGLFQKLLLFALCFPNLILPFQLSSLVFN-HADTNHHCNTDWILKADPNLTKEEQLNLTLPR 74

  Fly    77 KQDGSFENCFMYNVPYDSNAT----NDANQTRSPIPCNNGWIYDRKEVPYE-SIATEYNWVCDKR 136
            ..||||..|.||. |.|.|.:    ...|||.:   |.:||:::  :..|| :|.|:::.||:..
Zfish    75 LSDGSFNPCQMYK-PVDWNLSAIQEYGLNQTTT---CTDGWVHN--DTIYEATIVTDFDLVCENV 133

  Fly   137 DFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAG 201
            :....:..|:|.|.:||.:.||..::..||..|..:.....:|...|:.:..:|..:..|:|:.|
Zfish   134 NIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLMLIFTVVTGLSPNFYVYLVSQFING 198

  Fly   202 LSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVF 266
            :.:....:...||..|.:|:..|:....|: .....||..:...:.|.:.:||....::|.||..
Zfish   199 VGLGGFRINSIILASEWIGVAQRSYAACLS-QVLAALGQVMFLAVVYFVRDWRLDQFIMAGPIGI 262

  Fly   267 MILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEM-------RECYELKFANE 324
            :::.....|||..||:..|:.....:::::||..|.:.:.|.:..|:       :...::.|.:.
Zfish   263 VVIYIWFLPESARWLLDRGRTKDAKKLIQKAAAVNKRAVPESLVEEVLKEKPVEKGGIKILFGSR 327

  Fly   325 QLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGI 389
            .|.|.:.::    ||           .|..:.|||.:....|.....|||:|..:..|.|||...
Zfish   328 VLRKYFLAI----TF-----------AWCALNLAYYSLSLNVGKFGLDIFLTQLIFGLSEIPVHF 377

  Fly   390 VPMLLLDRIGRKP--MMSAVM-----LLCAA----SSLFVGILKGHWNASTAAIAARFFATMAYN 443
            :.|..|:.:||||  ::|.|:     ||..|    ||:.:.:|         |...||....|.:
Zfish   378 LCMWSLEVVGRKPSLIVSLVLGGCLCLLTVAVPQNSSIAIAVL---------ATCGRFLMNAAGS 433

  Fly   444 VGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFL 508
            |...:..|:.||.:|.....:.:...:.|::|||:|.....::..:||.:|:.:::...:....|
Zfish   434 VCNVYFQELFPTSIRQTATGLGSTAARAGSMLSPVVNMLEIFHFSIPMVVISSLALASGVTAFLL 498

  Fly   509 PETKGATMPQTLDEAE-KR-------WTLRCRDRKINE 538
            |||:...:|.:.:||| ||       .|..|.|.|:.:
Zfish   499 PETRRTELPASTEEAEGKRKPKLTSPATRDCEDTKVTK 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	137/528 (26%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	90/385 (23%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	136/526 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588899
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950