DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and slc22a7b.3

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_001337264.3	Gene:	slc22a7b.3 / 100001772	ZFINID:	ZDB-GENE-131120-103	Length:	546	Species:	Danio rerio

Alignment Length:	545	Identity:	151/545 - (27%)
Similarity:	269/545 - (49%)	Gaps:	23/545 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KYENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELE------GLPE 66
            |:|:.:..|..||.|||.:|.......|:....:....|:..:|.:| |.:..|:      .|.|
Zfish     2 KFEDLITEINGFGRFQKMILCISFVGRFIIPCHFLLSNFIAAIPSHH-CDISFLDADGLFGNLTE 65

  Fly    67 SEQKNRGIPKKQDGSFENCFMYNVPYDSNATNDANQTRSP-IPCNNGWIYDRKEVPYESIATEYN 130
            .|:....:|.::|||..:|.|::.|......|.::.:..| :.|.|||.:|.... ..::||:::
Zfish    66 EERLIVSVPTQEDGSPVSCHMFSHPQFQLLINSSSSSDLPVVECQNGWHFDNSTF-ISTLATQWD 129

  Fly   131 WVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAA 195
            .|||.|........::|||.:.|...||.::|..||.|.|.::....|.....||....|..||.
Zfish   130 LVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTSFTMFAV 194

  Fly   196 SRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVV 260
            .||.:|.::....:...:|.||.|.|::|.|| ::..:..:.:|:..|..:||.|.:||...:.|
Zfish   195 LRFFSGFTITGIVIVSSVLNLEWVDIEHRRLV-SIIDSMAWAVGSTSLALIAYFIRDWRWLTVAV 258

  Fly   261 ALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMR-ECYELKFANE 324
            ..|:|...:.....|||..||::.|.|::....:.:.|..|.|   .||.|.:: |...:. .::
Zfish   259 TSPLVLCTILWWWVPESARWLIANGDVEKAHYYLHKCAVMNRK---AEVTSRIKPEALAIS-VSD 319

  Fly   325 QLGKQYTSLDLFKTFPRLVVLTILIVT-WMTVA-LAYDAHVRVVEILDTDIFITFSLSSLVEIPA 387
            |..|:||.|||.:| |::..|.:|..| |..|| :.|...:.:.. ...::::|..:...:|:|:
Zfish   320 QGKKKYTYLDLVRT-PKMRKLAMLTGTVWFCVATMTYGISLNITG-FGLNMYLTQFVYGAIEVPS 382

  Fly   388 GIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGIL--KGHWNAST-AAIAARFFATMAYNVGQQWA 449
            .::...||::|||:...:...|. |..||.:.|.  |..|...| .|:..:.||..|:.....::
Zfish   383 KLIVYYLLEKIGRRKTEAGAQLF-AGISLMINIFIPKDQWIGRTVVAVLGKGFAVAAFCTIVLYS 446

  Fly   450 SEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGA 514
            ||:.|||||..|:...:.:.::|..::||||....::......|:..|::|.:::...||||:..
Zfish   447 SELYPTVLRQNGMGYNSFLARLGVSVAPLVLLLDTFWGQFSQTILCSVALIASVVAWNLPETRDR 511

  Fly   515 TMPQTLDEAEKRWTLRCRDRKINED 539
            .:|:|:::.|.......:|::..|:
Zfish   512 CLPETIEDVEGTGKTPNKDQEKQEN 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	144/514 (28%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	104/373 (28%)
slc22a7b.3	XP_001337264.3	2A0119	12..516	CDD:273328	144/513 (28%)
slc22a7b.3	XP_001337264.3	MFS	141..506	CDD:119392	104/372 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850