DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and zmp:0000001102

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_001340340.6	Gene:	zmp:0000001102 / 100000058	ZFINID:	ZDB-GENE-140106-62	Length:	560	Species:	Danio rerio

Alignment Length:	534	Identity:	145/534 - (27%)
Similarity:	262/534 - (49%)	Gaps:	31/534 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KYENFLLFIGDFGPFQKRLLFWM------MPAAFLFAFTYFGQIFMILLPKNHWCRVREL--EGL 64
            |::|.|.....||.:|..|:..:      :|..||.      ..|:..:|.:| |.:..|  :||
Zfish    12 KFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLL------NNFIAAIPSHH-CDISSLDADGL 69

  Fly    65 PESEQKNR---GIPKKQDGSFENCFMYNVPYDSNATNDANQTRSP-IPCNNGWIYDRKEVPYESI 125
            ....||.|   .:|.::||:..:|.|:..|......|.::.:..| :.|.|||.:|.... ..::
Zfish    70 GNLTQKERLIVSVPAQEDGTPASCHMFAHPQFQLLINSSSSSALPVVECQNGWHFDNSTF-ISTL 133

  Fly   126 ATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDF 190
            ||:::.|||||.....|..::|||.:.|.:.||.:.|..||...|.::...|::....|.....:
Zfish   134 ATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSY 198

  Fly   191 PCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRH 255
            ..|||.||:.||::........:|::|.|..|:||.:| |..:..:::|..||...|:::::||.
Zfish   199 IMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMG-LFGSMSWSIGNMLLAGFAFMVTDWRL 262

  Fly   256 YAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMR-ECYEL 319
            ..::|..|:.....|....|:|..||::.||.:...:.:.:.|..|.::   :..|.:: |....
Zfish   263 LIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRL---DFTSRVKPETLST 324

  Fly   320 KFANEQLGKQYTSLDLFKTFPRLVVLTILI-VTWMTVALAYDAHVRVVEILDTDIFITFSLSSLV 383
            ....:..|..||.|||.|| |:|..||:.. :.|..||..|......:.....|.::|..:.:.:
Zfish   325 VVTVDHRGHSYTYLDLVKT-PQLRKLTLFTGIVWYGVASTYYGISLNITGFGLDPYLTHFIYAAI 388

  Fly   384 EIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGIL--KGHWNASTA-AIAARFFATMAYNVG 445
            |:||.|:....|:::||:...:..::| ....:.:.|:  ..:|...|. |:..:..:..::...
Zfish   389 EVPAKILVYFSLNKVGRRNTQTGTLVL-TGFCILINIITPTEYWTFRTVIAVLGKGLSEASFTTV 452

  Fly   446 QQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPE 510
            ..:.:|:.|||:|..||...|.|.:|||.:|||::.....::.||..|...:::...:|.|.|||
Zfish   453 ILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLLPEVIFCSMAIFCGIIALLLPE 517

  Fly   511 TKGATMPQTLDEAE 524
            |..|::|:|:::.|
Zfish   518 TNNASLPETVEDIE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	140/518 (27%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	97/372 (26%)
zmp:0000001102	XP_001340340.6	Sugar_tr	22..526	CDD:331684	140/517 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010