DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf133 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	NP_937894.1	Gene:	Rnf133 / 386611	MGIID:	2677436	Length:	339	Species:	Mus musculus
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	232	Identity:	49/232 - (21%)
Similarity:	79/232 - (34%)	Gaps:	89/232 - (38%)

- Green bases have known domain annotations that are detailed below.

Mouse   104 LIERGGCAFTQKIKVASEHGARGVIIYNFPGTGNQVFPMSHQAFEDIVVVMIGNIKAYFTFYHIR 168
            |::||.|.:..|...|...|.:|||:      |:...|.|.:     :..|:...|...:..||.
pombe   146 LVQRGKCTYFDKALEAQRLGFKGVIV------GDNRSPSSFR-----LHYMVAPDKVDESKVHIP 199

Mouse   169 RLWVARIE-NRRWKRLT---RELKKAFGQ---------------------------LQVR----- 197
            .|:|:... |..|..|.   |:..|.:.:                           |.:|
pombe   200 SLFVSTSSYNLLWSDLLHSYRQPLKLYAKPEELGDMFWPFLLCFSPSIIMLITVQALAIRKFIRT 264

Mouse   198 ------------------VLKEG----DEEVNPNADS-------------------CVICFEAYK 221
                              :.:||    :||:..:..:                   ||||.|::.
pombe   265 YRTKSKTRRFIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECVICLESFT 329

Mouse   222 PNEIVRILTCKHFFHKNCIDPWILAH-GTCPMCKCDI 257
            ..:.|..|.|||.||:.||..||:.: ..||.|..::
pombe   330 KGDKVVALPCKHEFHRPCIAKWIVDYRHACPTCNTEV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf133	NP_937894.1	PA_GRAIL_like	43..159	CDD:239037	14/54 (26%)
Rnf133	NP_937894.1	zf-RING_2	211..254	CDD:290367	18/62 (29%)
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	49/232 (21%)
		Peptidases_S8_S53	<144..211	CDD:299169	20/75 (27%)
		zf-RING_2	320..362	CDD:290367	18/41 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810