Protein Alignment Rnf133 and H10E21.5

DIOPT Version :9

• Sequence 1: NP_937894.1
• Gene: Rnf133 / 386611
• MGIID: 2677436
• Length: 339
• Species: Mus musculus
• Sequence 2: NP_497129.1
• Gene: H10E21.5 / 175169
• WormBaseID: WBGene00019185
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 360
• Identity: 87/360 - (24%)
• Similarity: 143/360 - (39%)
• Gaps: 80/360 - (22%)

Mouse    16 FWLLRFSFIWLVSQKCCTASAVWTAYMNI------SFHVGNRMLSEL---GETGVFGRSSILKRV 71
            |:|:...|:         .|:|...|.|:      |..|...:.:||   .:.|  |.|:.|...
 Worm    11 FFLIFMRFL---------QSSVDAVYTNVKLQCIDSEEVYGTLQTELTFSNKDG--GGSTFLPAY 64

Mouse    72 AGVVVPP------------EGKIQNACD-----PNTTFIL-----PRNKEPW------IALIERG 108
            ..:..|.            :..|||...     |....|:     |.|:..|      ::.|...
 Worm    65 TDLCAPDMKFDDSQRVFFCKNCIQNCLSRVETAPKNILIVADVKAPNNRVSWFHVQTPVSNIRES 129

Mouse   109 G--CAFTQKIKVASEHGARGVIIYNFPGTGNQVFPMSHQAFEDIVVVMIGNIKAYFTFYHIRRLW 171
            |  |.......:.|........:.:|..|......:|      .:::|:.:: |:..||:::|..
 Worm   130 GKQCNVENSNAMQSPEETSTDALRSFSKTSVLFVSIS------FIILMVISL-AWLVFYYVQRFR 187

Mouse   172 VARIENRRWKRLTRELKKAFGQLQVRVLKEG-DEEVNPNADSCVICFEAYKPNEIVRILTCKHFF 235
            .|..::|..:||....:||..::....:..| .:|:.   ..|.:|.:.|:..:::|:|.|||.:
 Worm   188 YAHAKDRLQRRLFNAARKALTRIPTMTITPGMTQELQ---SDCAVCLDPYQLQDVIRLLPCKHIY 249

Mouse   236 HKNCIDPWILAHGTCPMCKCDILKALGIQMDIEDGTDSLQVLMSNELPGTLSPVEEETNYELPPA 300
            ||:|||||:|.|.||||||.||||..|...||.:..         ::|.....:.::....|...
 Worm   250 HKSCIDPWLLEHRTCPMCKNDILKHFGYWNDIRNDI---------QMPTNSRGIADDFTIRLELG 305

Mouse   301 RTSSKVTHVQEHPTSSANAGSQPPEAEETSHPSHG 335
            .        |||...||:..|  |||...:..|.|
 Worm   306 E--------QEHQAPSADVIS--PEANSDTSDSQG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf133	NP_937894.1	PA_GRAIL_like	43..159	CDD:239037	26/154 (17%)
		zf-RING_2	211..254	CDD:290367	21/42 (50%)
H10E21.5	NP_497129.1	HRD1	<150..325	CDD:227568	57/203 (28%)
		RING-H2_GRAIL	226..273	CDD:319582	25/46 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm16989
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.970