Protein Alignment DNApol-epsilon58 and pole2

DIOPT Version :9

• Sequence 1: NP_647995.1
• Gene: DNApol-epsilon58 / 38661
• FlyBaseID: FBgn0035644
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_775353.1
• Gene: pole2 / 192320
• ZFINID: ZDB-GENE-020419-16
• Length: 527
• Species: Danio rerio
• Alignment Length: 526
• Identity: 204/526 - (38%)
• Similarity: 311/526 - (59%)
• Gaps: 10/526 - (1%)

  Fly     3 VDLLPLRKRITNTFKLCGFLIRSENSSYLAEQLLPFDAAERDKWLTVITENLQSQKLLTPHVERA 67
            :|...:::::...||:.|.::|.|:|.:|.:.|.....||.::.|..:.::::.|.|.:..|:..
Zfish     1 MDARRVKQKVNAGFKMRGLILRPESSRFLLQVLESVSPAELEEVLERVLDSVEKQPLSSSMVDLC 65

  Fly    68 ALEKAINELNRVGLDEGETVFALIDAFTVPRFRYNQRIKKF---ELDTQP-RQLLTAPRMKSDYM 128
            .||.|:.:.::...:..:.||.:|.||.||||.::...|||   .:...| .:|....|.|::..
Zfish    66 VLEAAVQDCSQSCDETIDHVFNIIGAFDVPRFIFSTERKKFVPISMTNHPLPKLCGQARDKAELF 130

  Fly   129 QQRYAMLLQKTLRHDLFAPAVIQDGVGAEAQAKKFKLQFAENLLATSA-MKEAVVLGLLTQLKEG 192
            ::||.:|.|:|.||:||.|.||  |...:....||:|:..|.||.:|| :.|.:|||::|||:||
Zfish   131 RERYTILQQRTHRHELFTPPVI--GSAQDEGRNKFQLKTVEALLCSSARLGEVIVLGMITQLREG 193

  Fly   193 KFYVEDPTGCVQLDLTGARFHAGFFCEGCFVLAEGNYNNGVLKVDGLGFPPAEPANSSRAFFGTA 257
            |||:|||:|.||||::.|:||:|.:.|.|||||||.|.:.|..|...||||.||::.:||:||..
Zfish   194 KFYLEDPSGTVQLDISKAQFHSGLYTESCFVLAEGWYEDSVFHVSAFGFPPTEPSSFTRAYFGNV 258

  Fly   258 NTWGGESAKLLKYSAGLQELERTNTETTIVFLSDVRLDLPVVMEKLRQLFVGYDSCPPQAIVLMG 322
            |.:||.|:..:|.||.|::||..|.:...|.:|||.||...|:||:..:|.||.:.||...:..|
Zfish   259 NFFGGPSSTAVKASAKLKQLEEENEDAMFVLVSDVWLDSVEVLEKIHTMFSGYSALPPTCFIFCG 323

  Fly   323 PFTASTRNHHELRHHLDALGGLA-AGCE--QLKKQTDLILVPSSEDPTAPNILPRAPIPECLAAG 384
            .|:::.....:||...|:...|| ..||  .:...:..:.||..|||....:|||.|:.|.:...
Zfish   324 SFSSAPYGRTQLRSLRDSFKALADLICEFPSIHSSSRFVFVPGPEDPGPGAVLPRPPLAEHITEE 388

  Fly   385 LLKAWPRTQLATNPCRLQYCTQQIVVCRLDLMAKFCRNTLHFPEDTSQIEQHFARTIVCQGHLVP 449
            ..:..|.:...|||||:|||:|::|:.|.||:.|.|||....|..:..|..||.:|::.||||.|
Zfish   389 FQQRVPLSVFTTNPCRIQYCSQELVIIREDLVNKMCRNCERLPSSSLDIPTHFVKTVLSQGHLTP 453

  Fly   450 IHPIAMPVHWDYDPALWLYPLPDLIVMGDSCQSFSSSQHGCTVLNTGSFVKSKFAFKVYIPATRT 514
            :.....||.|.||..|.|||:||:||..|....|:.....|..:|.|||.:|.|:||||.|::||
Zfish   454 LPLYVCPVFWAYDHTLRLYPVPDVIVFADKYDPFNICNTDCLCINPGSFPRSGFSFKVYYPSSRT 518

  Fly   515 IEDSEI 520
            :|||::
Zfish   519 VEDSKL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-epsilon58	NP_647995.1	Dpoe2NT	7..76	CDD:371965	17/68 (25%)
		DNA_pol_E_B	287..484	CDD:367778	75/199 (38%)
pole2	NP_775353.1	Gasdermin	<2..161	CDD:282457	47/160 (29%)
		Dpoe2NT	3..73	CDD:289021	17/69 (25%)
		DNA_pol_E_B	288..487	CDD:281968	75/198 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4761
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2015
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2995
OMA	1	1.010	-	-		QHG54736
OrthoDB	1	1.010	-	-		D249486at33208
OrthoFinder	1	1.000	-	-		FOG0004867
OrthoInspector	1	1.000	-	-		oto39355
orthoMCL	1	0.900	-	-		OOG6_102104
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4545
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.880