Protein Alignment CG13287 and Prdm8

DIOPT Version :10

• Sequence 1: NP_001261454.1
• Gene: CG13287 / 38660
• FlyBaseID: FBgn0035643
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_084223.2
• Gene: Prdm8 / 77630
• MGIID: 1924880
• Length: 688
• Species: Mus musculus
• Alignment Length: 582
• Identity: 147/582 - (25%)
• Similarity: 200/582 - (34%)
• Gaps: 245/582 - (42%)

  Fly    22 PQHAELRIST-----SPQQSPQQNQ-----TTNHNNNNETPTSPPGGKTTLKRAFDVAFLMMPDE 76
            |..|.||...     |...:||..|     |.:|....       ||
Mouse   168 PYVAHLRFRCPKRLHSTDANPQDEQGGGLGTKDHGGGG-------GG------------------ 207

  Fly    77 RIKQKQAEKQARLQEA-------------LHHH-------------------------HHQQQQQ 103
              |::|.::|.:.|||             :||:                         |:..::.
Mouse   208 --KEQQQQQQQQQQEAPLIPGPKFCKAGPIHHYPASSPEASNPPGSAGAGSAKPSTDFHNLAREL 270

  Fly   104 QMS------------------HYPTDLSPRGTSS-------QPPSPAALE--YISLLEARQRYPQ 141
            :.|                  |...:|||.|.::       :.|..||.|  ...|...|.|:.:
Mouse   271 ENSRGSSSCVAAPGVGSGGSGHQEAELSPDGVATGGCKGKRRFPEEAAAEGGGAGLAGGRARFSE 335

  Fly   142 ISIR--------SPRVYDDPSVVIPLVD-----SPEAPSTSSPPPPMRSAFTKV----------- 182
            ..:.        :|:.|........|.:     :|.:|.|..   ..||||.:|
Mouse   336 RPLATSKEELVCTPQQYRAAGSYFGLEENGRLFAPPSPETGE---AKRSAFVEVKKAGRAVGLQE 397

  Fly   183 ----------------ASSSLSTSSSSPSTTSRLESPVDAGAPPLSPDQLSCHSISPPLVTPPPR 231
                            |...::...|:.|:|....||   |||             ..|:.|.|
Mouse   398 EAAATDGAGGTAEDPDAGGGVAGGGSNGSSTPAAGSP---GAP-------------EKLLAPRP- 445

  Fly   232 TNSGGQNPNPLP-ANPIVYHNFRPEYQFNG---------------------------------AF 262
               ||..|..|. .:|.....|....|..|                                 :|
Mouse   446 ---GGSLPGRLEGGSPARGSAFTSVSQLGGGGGAGTAGTAGGSGGGQTAASDERKSAFSQPARSF 507

  Fly   263 QAVNPMQALQAQQRLKQQLLYTRPPGPGNPNGGGPT-----------------MQANSPPGP--- 307
            ..::|:.       |.|:|....|..||  :|.|||                 ...|...||
Mouse   508 SQLSPLV-------LGQKLGALEPCHPG--DGVGPTRLYPAAADPLAVKLQGAADLNGACGPLAS 563

  Fly   308 --------PSEFLHA---YP--GFAPPPHPFAVSQPLQNPAAAAILSTLIPPTLASTFTLTAQNV 359
                    .|.||:|   :|  ..|......|.:.|||....:|:  ||:||:..| ..|.|||.
Mouse   564 GGGGGLPKQSPFLYATAFWPKSSAAAAAAAAAAAGPLQLQLPSAL--TLLPPSFTS-LCLPAQNW 625

  Fly   360 CAKCNISFRMTSDLVYHMRSHHKSEVACDP-NRRKREEKLRCPVCQETFRERHHLTRHMTAH 420
            |||||.|||||||||||||||||.|.|.:| .:|:|||||:||:|.|:|||||||:||||:|
Mouse   626 CAKCNASFRMTSDLVYHMRSHHKKEYAMEPLVKRRREEKLKCPICNESFRERHHLSRHMTSH 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13287	NP_001261454.1	C2H2 Zn finger	360..380	CDD:275368	18/19 (95%)
		zf-C2H2_2	363..>418	CDD:463690	41/55 (75%)
		zf-C2H2	399..420	CDD:395048	15/20 (75%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
Prdm8	NP_084223.2	PR-SET_PRDM8	6..138	CDD:380969
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..309		22/151 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..506		20/128 (16%)
		C2H2 Zn finger	626..646	CDD:275368	18/19 (95%)
		zf-C2H2	666..687	CDD:395048	15/20 (75%)
		C2H2 Zn finger	667..687	CDD:275368	15/19 (79%)