DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13287 and prdm8

DIOPT Version :9

Sequence 1:	NP_001261454.1	Gene:	CG13287 / 38660	FlyBaseID:	FBgn0035643	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_998575.1	Gene:	prdm8 / 406719	ZFINID:	ZDB-GENE-040426-2747	Length:	502	Species:	Danio rerio

Alignment Length:	336	Identity:	100/336 - (29%)
Similarity:	152/336 - (45%)	Gaps:	73/336 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 QRYPQISIRSPRVYDDPSVVIPLVDSPEAPSTSS-------------PPPPMRSAF---TKVASS 185
            |:.|::. |..:|.|..::...|.|...:.|:..             .|...::..   |.:.:.
Zfish   187 QQKPEVK-RHRKVIDFHNIARDLEDKMNSSSSEDTTILRKRKQEPFLTPKSKKTVLLEKTNITNE 250

  Fly   186 SLSTSSSSPSTTSR-LESPVDAGAPPLSPDQLSCHSISPPLVTPPPRTNSGGQNPNPLPANPIVY 249
            |.:|:::......| |..|.|..  ..:..::|.:|....:...|       :.|||..::..:
Zfish   251 SNTTNANKDCRAFRDLSEPTDNA--QTNESKISKNSAFTEVRKAP-------EPPNPEKSSRDI- 305

  Fly   250 HNFRPE--YQFN-GAFQAVNPMQALQAQQRL-----KQQLLYTRPPGPGNPNGGGPTMQANSPPG 306
              ..||  .|.| .||..|.|..|...|:..     |:.|...:.|.|.:.:....:.::.|..|
Zfish   306 --MAPEVGLQSNCSAFSFVVPKSARSEQKSAFCEPSKRALAEAQNPSPPDTDNSLDSFKSKSSLG 368

  Fly   307 P---------PSEFLHAYPG--------------FAPPPHPFAVSQPLQNPAAAAILSTLIPPTL 348
            .         |::...::.|              :||.....|:...||:.::.    ||:||
Zfish   369 YRNVLASHLFPTDLAGSHAGGGMSAPLTSGGSYYYAPEHWTRAIGGQLQSTSSL----TLLPP-- 427

  Fly   349 ASTFT---LTAQNVCAKCNISFRMTSDLVYHMRSHHKSEVACDPN-RRKREEKLRCPVCQETFRE 409
              |||   ::.||.|||||:|||||||||:|||||||.|.|.:.. ||:|||||.||:|.|.|||
Zfish   428 --TFTPLGVSVQNWCAKCNLSFRMTSDLVFHMRSHHKKEFAAEAQVRRRREEKLTCPICHEYFRE 490

  Fly   410 RHHLTRHMTAH 420
            ||||:||||:|
Zfish   491 RHHLSRHMTSH 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13287	NP_001261454.1	C2H2 Zn finger	360..380	CDD:275368	17/19 (89%)
		zf-C2H2_2	363..>418	CDD:289522	40/55 (73%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
prdm8	NP_998575.1	SET	32..129	CDD:279228
		C2H2 Zn finger	440..460	CDD:275368	17/19 (89%)
		C2H2 Zn finger	481..501	CDD:275368	15/19 (79%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006844
OrthoInspector	1	1.000	-	-		otm25623
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16516
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.990