Protein Alignment CG18586 and CMR2

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_014736.1
• Gene: CMR2 / 854260
• SGDID: S000005619
• Length: 1648
• Species: Saccharomyces cerevisiae
• Alignment Length: 628
• Identity: 125/628 - (19%)
• Similarity: 226/628 - (35%)
• Gaps: 183/628 - (29%)

  Fly    77 VASYMR-----NMGLGQTDIVGVMGRHTTHQSAVAYACFFNG---TPLHALHNAYEEACIAKLFG 133
            ||.:::     .:.|...|.:.:|..::....|:..||.:..   .||.::..:..|..:..|..
Yeast  1031 VAGFLKKIVGSKIPLKHGDPIIIMCENSVEYVAMIMACLYCNLLVIPLPSVKESVIEEDLKGLVN 1095

  Fly   134 IT---KPRLIFCDGDEYEKVKSATKDLQVTIVTMRNH----PR----GSVRIQDVLTTPVMQNF- 186
            |.   |.:.:|.|.    |:.|...|..|.....:.:    |:    ..|:.::.||..:.:|.
Yeast  1096 IIQSYKVKRVFVDA----KLHSLLNDNNVVNKCFKKYKSLIPKITVFSKVKTKNALTVSMFKNVL 1156

  Fly   187 -QPLRLKDG--IDHTLAIL----SSSGTSGFPKAVTIS---NSHKIIVDYMAINNSNIQYT---- 237
             |....|.|  |..|..::    ....||.....:|.|   |:.||:.:.:.:.|::..::
Yeast  1157 KQKFGAKPGTRIGMTPCVVWVNTEYDVTSNIHVTMTHSSLLNASKIVKETLQLRNNSPLFSICSH 1221

  Fly   238 SSTLDWCSGLSMAITSG----VFSTTSIIADCDFDPGLFCRAIGKYRISMVLL-----------S 287
            :|.|.:.....:.|.:|    :||.|.::.    ||..|...:....:..:.|           :
Yeast  1222 TSGLGFMFSCLLGIYTGASTCLFSLTDVLT----DPKEFLIGLQNLNVKDLYLKLETLYALLDRA 1282

  Fly   288 SSYLAIFANCPE-FESA---DLSSLNYVIFGG------------SSCSLEVQRKVRSRLSHDCLN 336
            ||.:..|.|..| ..||   ...||...:|.|            ...::|...|..|.:|..|..
Yeast  1283 SSLIEGFKNKKENINSAKNNTSGSLREDVFKGVRNIMIPFPNRPRIYTIENILKRYSTISLSCTQ 1347

  Fly   337 FCY-------GLTELNS---AGSVNLNFDE-----------KPNSVGRAIRGIKIKVIDE----- 375
            ..|       .|..|.|   ...|:|..|.           .||.|.   .|..||:.|.
Yeast  1348 ISYVYQHHFNPLISLRSYLDIPPVDLYLDPFSLREGIIREVNPNDVS---AGNYIKIQDSGVVPV 1409

  Fly   376 -------QGEAQEPNVVGE----------------ICFHNSQKWAGYYKNPDETRQ--------I 409
                   ..|...|.|.||                :|..:..|   .||:|..|.|        :
Yeast  1410 CTDVSVVNPETLLPCVDGEFGEIWCCSEANAFDYFVCNSSKNK---LYKDPFITEQFKSKMKSEV 1471

  Fly   410 QDSENWIHTGDLGYV------DKDG------YLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNV 462
            .::.:::.|||||::      :..|      .|||:..:.:.::...:.::.|::|..:.::.:.
Yeast  1472 NNTLSYLRTGDLGFIKNVSCTNSQGEVVNLNLLFVLGSIHESIEILGLTHFVSDLERTVKDVHSD 1536

  Fly   463 LEACVF----GI----------WDPVNGDEA---AASLVKKPGTQLEAQDVVEYVR-KRITAKFK 509
            :.:|:.    |:          .:|:.|:..   .:.|:.|.|..|   |:..:|| |.|:.|
Yeast  1537 IGSCLIAKAGGLLVCLIRCKERHNPILGNLTTLIVSELLNKHGVIL---DLCTFVRTKGISPK-- 1596

  Fly   510 QLNGGALIVDQIVRSGNRKTNRSA-------VKEHFLKNYNNN 545
               ..::|::  |.:.||.:...|       ::..|..||..|
Yeast  1597 ---NSSMIME--VWAKNRASIMQAWFDQKIQIEAQFGINYGEN 1634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	122/622 (20%)
		AFD_class_I	55..530	CDD:302604	120/604 (20%)
CMR2	NP_014736.1	DMAP_binding	5..121	CDD:368923
		AFD_class_I	179..893	CDD:418409
		Dip2	1004..1626	CDD:341231	121/618 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900