DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18586 and OPCL1

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	142/541 - (26%)
Similarity:	238/541 - (43%)	Gaps:	45/541 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEMEVKQKLLNAMCTYDDKLKIWSGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVL 65
            ||.:..:....|:..|:..|       ..|....||.|:....|.....:...||.|..:....|
plant     1 MASVNSRSGFCNSNSTFYSK-------RTPIPLPPNPSLDVTTFISSQAHRGRIAFIDASTGQNL 58

  Fly    66 TREDLHMNAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNG---TPLHALHNAYEEAC 127
            |..:|......||..:..:|:.:..:|.::..::.....|..:....|   |..:.|:.:.|
plant    59 TFTELWRAVESVADCLSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNE--- 120

  Fly   128 IAKLFGITKPRLIFCDGDEYEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPL--R 190
            |||....:.|.|.|.......|:.:|.|.|  .||.|......||  .||.....|...:|.  |
plant   121 IAKQIKDSNPVLAFTTSQLLPKISAAAKKL--PIVLMDEERVDSV--GDVRRLVEMMKKEPSGNR 181

  Fly   191 LKDGIDH--TLAILSSSGTSGFPKAVTISNSHKI-----IVDYMAINNSNIQYTSSTLDWCS--- 245
            :|:.:|.  |..:|.||||:|..|.|..|:.:.|     ||:....::...::.      |:
plant   182 VKERVDQDDTATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFI------CTVPM 240

  Fly   246 ----GLSMAITSGVFSTTSIIADCDFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESA--D 304
                ||:...|..:...::||....|:......|||||:.:.:.|....|....|..:...|  |
plant   241 FHIYGLAAFATGLLAYGSTIIVLSKFEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKYD 305

  Fly   305 LSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDE--KPNSVGRAIRG 367
            |||::.|:.||:..|.||......:.....:...|||||....|:.....:|  :..:.|:....
plant   306 LSSMHTVLCGGAPLSKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSAS 370

  Fly   368 IKIKVIDE-QGEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLF 431
            ::.:::|. .|:...|...||:.........||:.|.:.|....|||.|:.||||.|:|:||::|
plant   371 MEGRIVDPVTGQILGPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYIDEDGFIF 435

  Fly   432 VIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQLEAQDV 496
            |:||||:::||:.....|:|:|.::...|.:.:|.|....|...|....|.:|:|.|:.|..:.:
plant   436 VVDRLKELIKYKGYQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSSLSEKTI 500

  Fly   497 VEYVRKRITAKFKQLNGGALI 517
            :|:|.|:: |.:|::...|.:
plant   501 MEFVAKQV-APYKRIRKVAFV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	136/507 (27%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	131/487 (27%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	136/509 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920