DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and AT1G20480

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_173472.1	Gene:	AT1G20480 / 838636	AraportID:	AT1G20480	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	133/535 - (24%)
Similarity:	239/535 - (44%)	Gaps:	47/535 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEMEVKQKLLNAMCTYDDKLKIWSGREAPSLFSPNLSI------------GEIIFGDMVNNPKLI 54
            :|:|.:...::....:.:...|:..:..|....||..:            |:.:|.|.|...:
plant    12 SEIESRTLAVDRKSGFCESTSIFYSKREPMALPPNQFLDVTSFIASQPHRGKTVFVDAVTGRR-- 74

  Fly    55 AQISITEDIVLTREDLHMNAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLHAL 119
                      |:..:|.:...|||..:..:|:.:.::|.::..::.....|:.:....|..:...
plant    75 ----------LSFPELWLGVERVAGCLYALGVRKGNVVIILSPNSILFPIVSLSVMSLGAIITTA 129

  Fly   120 H--NAYEEACIAKLFGITKPRLIFCDGDEYEKVKSATK-DLQVTIVTMRNHPRGS----VRIQDV 177
            :  |..:|  |:|..|.::|.|.|.......|:.:|:. :|.|.::...:.|..|    |::...
plant   130 NPINTSDE--ISKQIGDSRPVLAFTTCKLVSKLAAASNFNLPVVLMDDYHVPSQSYGDRVKLVGR 192

  Fly   178 LTTPVMQNFQPLRLKDGI--DHTLAILSSSGTSGFPKAVTISNSHKIIVDYMAINNSNI---QYT 237
            |.|.:.......|:|..:  |.|.|:|.||||:|..|.|.:  ||:.::..:....:..   |.|
plant   193 LETMIETEPSESRVKQRVNQDDTAALLYSSGTTGTSKGVML--SHRNLIALVQAYRARFGLEQRT 255

  Fly   238 SSTLDWCS--GLSMAITSGVFSTTSIIADCDFDPGLFCRAIGKYRIS-MVLLSSSYLAIFANCPE 299
            ..|:..|.  |.....|..:....:|:....||......|:..:|.| :.|:....:|:.....|
plant   256 ICTIPMCHIFGFGGFATGLIALGWTIVVLPKFDMAKLLSAVETHRSSYLSLVPPIVVAMVNGANE 320

  Fly   300 FESA-DLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDE--KPNSV 361
            ..|. |||||:.|:.||:..|.||..|.........:...|||||..:..:...|.:|  :..:.
plant   321 INSKYDLSSLHTVVAGGAPLSREVTEKFVENYPKVKILQGYGLTESTAIAASMFNKEETKRYGAS 385

  Fly   362 GRAIRGIKIKVID-EQGEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVD 425
            |.....::.|::| :.|.....|..||:...:.....||:||.:.|....|||.|:.||||.|:|
plant   386 GLLAPNVEGKIVDPDTGRVLGVNQTGELWIRSPTVMKGYFKNKEATASTIDSEGWLKTGDLCYID 450

  Fly   426 KDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQ 490
            .||::||:||||:::|.......|:|:|.::...|.:.:|.|..|.|...|....|.:|:|.|:.
plant   451 GDGFVFVVDRLKELIKCNGYQVAPAELEALLLAHPEIADAAVIPIPDMKAGQYPMAYIVRKVGSN 515

  Fly   491 LEAQDVVEYVRKRIT 505
            |...:::.:|.|:::
plant   516 LSESEIMGFVAKQVS 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	129/502 (26%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	123/470 (26%)
AT1G20480	NP_173472.1	PLN02574	27..562	CDD:215312	131/520 (25%)
AT1G20480	NP_173472.1	4CL	43..557	CDD:213272	129/504 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920