DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18586 and AAE5

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_197141.1	Gene:	AAE5 / 831498	AraportID:	AT5G16370	Length:	552	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	132/571 - (23%)
Similarity:	234/571 - (40%)	Gaps:	110/571 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SPNLS-IGEI-----IFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYMRNMGLGQTDIV 92
            ||.|: ||.:     ::||..:       |....:.|.|..:.::..:||||.:.::|:|::|:|
plant    11 SPPLTPIGFLERAATVYGDCTS-------IVYGSNTVYTWRETNLRCLRVASSLSSIGIGRSDVV 68

  Fly    93 GVMGRHTTHQSAVAYACFFNGTPLHALHNAYEEACIAKLFGITKPRLIFCD----GDEYEKVKSA 153
            .|:..:|.....:.:|...:|..|:.::...:...::.|......:|:|.|    ....|.:...
plant    69 SVLSPNTPAMYELQFAVPMSGAILNNINTRLDARTVSVLLRHCGSKLLFVDVFSVDLAVEAISMM 133

  Fly   154 TKDLQVTI-VTMRNHPRGSVRIQDVLTTPVMQNFQPLRLKDGID----------HTLAILSSSGT 207
            |.|..:.: :..:....|...:.|  .|.....:..|..:..:|          ..:.:..:|||
plant   134 TTDPPILVFIADKEEEGGDADVAD--RTKFSYTYDDLIHRGDLDFKWIRPESEWDPVVLNYTSGT 196

  Fly   208 SGFPKAVTISNSHKIIVDYMAINNSNIQYTSSTLDW----------------CSGLSMAITSGVF 256
            :..||.|.  :.|:.|. .|:|:        |.:||                .:|.|........
plant   197 TSAPKGVV--HCHRGIF-VMSID--------SLIDWTVPKNPVYLWTLPIFHANGWSYPWGIAAV 250

  Fly   257 STTSIIADC--DFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCS 319
            ..|::   |  .||..|..|.|..:.::.:..:...|.:.:...||:..: ..:|.:..|....:
plant   251 GGTNV---CLRKFDAPLIYRLIRDHGVTHMCGAPVVLNMLSATNEFQPLN-RPVNILTAGAPPPA 311

  Fly   320 LEVQR--KVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKP--NSVG-------RAIRGIK---- 369
            ..:.|  .:...:||.     |||||  :|| :|::...||  |.:.       :|.:|::
plant   312 AVLLRAESIGFVISHG-----YGLTE--TAG-LNVSCAWKPQWNRLPASDRARLKARQGVRTVGF 368

  Fly   370 --IKVID-EQGEAQEPN--VVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGY 429
              |.|:| |.|.:.|.|  .||||....|....||.|:|..|.:.. ...|.:|||:|.:..|||
plant   369 TEIDVVDPESGRSVERNGETVGEIVMRGSSIMLGYLKDPVGTEKAL-KNGWFYTGDVGVIHSDGY 432

  Fly   430 LFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPG-TQLEA 493
            |.:.||.||::..........|:|.|:...|.|.|..|....|...|:...|.:..|.| ||...
plant   433 LEIKDRSKDIIITGGENVSSVEVETVLYTNPAVNEVAVVARPDVFWGETPCAFVSLKSGLTQRPT 497

  Fly   494 Q-DVVEYVRKRI-------TAKFKQLNGGALIVDQIVRSGNRKTNRSAVKE 536
            : :::||.||::       |..|         ||::.::...|..:..::|
plant   498 EVEMIEYCRKKMPKYMVPKTVSF---------VDELPKTSTGKVMKFVLRE 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	131/570 (23%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	124/536 (23%)
AAE5	NP_197141.1	ttLC_FACS_AEE21_like	12..539	CDD:341283	130/568 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810