DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and AT4G05160

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_192425.1	Gene:	AT4G05160 / 825864	AraportID:	AT4G05160	Length:	544	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	132/528 - (25%)
Similarity:	248/528 - (46%)	Gaps:	62/528 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GREA------PSLF---SPNLSIGEIIFGDMVNNP-KLIAQISITEDIVLTREDLHMNAMRVASY 80
            ||:.      |:|.   .||.|:...:|.:..:.| ||....|.|.| .||...|.....|:|..
plant     7 GRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKLAIADSDTGD-SLTFSQLKSAVARLAHG 70

  Fly    81 MRNMGLGQTDIVGVMGRHTTHQSAVAY-------ACFFNGTPLHALHNAYEEACIAKLFGITKPR 138
            ...:|:.:.|:|.:...: ::|..:.:       ..|....||:.::.      ::|....:.|:
plant    71 FHRLGIRKNDVVLIFAPN-SYQFPLCFLAVTAIGGVFTTANPLYTVNE------VSKQIKDSNPK 128

  Fly   139 LIFCDGDEYEKVKSATKDLQVTIVTMRNH---PRGS----VRIQDV--LTTPVMQ-NFQPLRLKD 193
            :|......::|:|..  ||.|.::..::.   |.||    :...:|  |:.||.: .|..::..|
plant   129 IIISVNQLFDKIKGF--DLPVVLLGSKDTVEIPPGSNSKILSFDNVMELSEPVSEYPFVEIKQSD 191

  Fly   194 GIDHTLAILSSSGTSGFPKAVTISNSHKIIVDYMAINNSNIQYTSSTLDWC-------SGLSMAI 251
                |.|:|.||||:|..|.|.:::.:.|....|...:.::......:..|       .||::..
plant   192 ----TAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVIT 252

  Fly   252 TSGVFSTTSIIADCDFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGS 316
            .|.:....::::...|:..|..:.|.|:|::.:.:........:.....:..|||||.|:..|.:
plant   253 YSQLQRGNALVSMARFELELVLKNIEKFRVTHLWVVPPVFLALSKQSIVKKFDLSSLKYIGSGAA 317

  Fly   317 SCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKP-------NSVGRAIRGIKIKVID 374
            ....::..:....:.:..|...||:||  :.|.|::   |.|       .|.|....|::.:::.
plant   318 PLGKDLMEECGRNIPNVLLMQGYGMTE--TCGIVSV---EDPRLGKRNSGSAGMLAPGVEAQIVS 377

  Fly   375 -EQGEAQEPNVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKD 438
             |.|::|.||..|||.........||..||..|::..|.::|:|||||||.::||.|:|:||:|:
plant   378 VETGKSQPPNQQGEIWVRGPNMMKGYLNNPQATKETIDKKSWVHTGDLGYFNEDGNLYVVDRIKE 442

  Fly   439 MLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQLEAQDVVEYVRKR 503
            ::||:.....|:|:|.::...|::|:|.|....|...|:...|.:|:.|.:.:..||:.:::.|:
plant   443 LIKYKGFQVAPAELEGLLVSHPDILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEQDIQKFIAKQ 507

  Fly   504 ITAKFKQL 511
            : |.:|:|
plant   508 V-APYKRL 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	128/510 (25%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	121/489 (25%)
AT4G05160	NP_192425.1	4CL	21..536	CDD:341230	128/514 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920