DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and 4CL5

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_188760.3	Gene:	4CL5 / 821677	AraportID:	AT3G21230	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	140/512 - (27%)
Similarity:	246/512 - (48%)	Gaps:	50/512 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PSLFSPN-LSIGEIIF----GDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYMRNMGLGQT 89
            |.:|.|| |.:.:.:|    ||...:......|......:||..|:..|..|:|:.:..:|:...
plant    34 PDIFIPNHLPLTDYVFQRFSGDGDGDSSTTCIIDGATGRILTYADVQTNMRRIAAGIHRLGIRHG 98

  Fly    90 DIVGVMGRHTTHQS----AVAY--ACFFNGTPLHALHNAYEE--ACIAKLFGITKPRLIFCDGDE 146
            |:|.::..::...:    ||||  |......|.:......::  |..||:. |||..|:
plant    99 DVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEIAKQAKASAAKMI-ITKKCLV------ 156

  Fly   147 YEKVKSATKDLQVTIVTMRNHPRGSVRIQD---VLTTPVMQNFQPLRLKDGI--DHTLAILSSSG 206
             :|:.:...|..:.:....:...|.|...|   |..|.:.|..:...||..|  :.|:|:..|||
plant   157 -DKLTNLKNDGVLIVCLDDDGDNGVVSSSDDGCVSFTELTQADETELLKPKISPEDTVAMPYSSG 220

  Fly   207 TSGFPKAVTISNSHKIIVDYMAI----NNSNIQYTSSTLDWC-------SGLSMAITSGVFSTTS 260
            |:|.||.|.|  :||.:|..:|.    .|.|:.:|::.:..|       ..|...:.|.:.:..:
plant   221 TTGLPKGVMI--THKGLVTSIAQKVDGENPNLNFTANDVILCFLPMFHIYALDALMLSAMRTGAA 283

  Fly   261 IIADCDFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSLEVQRK 325
            ::....|:..|....|.:|::::|.::...:..|...||.|..||||:..::.|.::...|::..
plant   284 LLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFIKSPETERYDLSSVRIMLSGAATLKKELEDA 348

  Fly   326 VRSRLSHDCLNFCYGLTELNSAGSV--NLNFDEKP-----NSVGRAIRGIKIKVID-EQGEAQEP 382
            ||.:..:......||:||   :|:|  :|.|.:.|     .:.|..||..::||:| |.|.:...
plant   349 VRLKFPNAIFGQGYGMTE---SGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTETGISLPR 410

  Fly   383 NVVGEICFHNSQKWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMY 447
            |..||||....|...||..:|:.|.:..|.:.|:||||:|:||.|..:|::||||:::|::....
plant   411 NKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQV 475

  Fly   448 YPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQLEAQDVVEYVRKRI 504
            .|:|:|.::...|::.:|.|..:.|.|..:...|.:.:..|:||...||..||.|::
plant   476 APAELEALLISHPSIDDAAVVAMKDEVADEVPVAFVARSQGSQLTEDDVKSYVNKQV 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	138/507 (27%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	132/482 (27%)
4CL5	NP_188760.3	PLN02246	20..567	CDD:215137	140/512 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920