Protein Alignment CG18586 and ACSM3

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_024306135.1
• Gene: ACSM3 / 6296
• HGNCID: 10522
• Length: 633
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 110/450 - (24%)
• Similarity: 174/450 - (38%)
• Gaps: 103/450 - (22%)

  Fly   148 EKVKSATKDLQVTIVTMRN-----------------HPRGSVRIQDVLT---TPVMQNFQPLRLK 192
            :.|.|..::|...::...|                 ||..|...:..||   |.::|..  |.|.
Human   182 DAVASKCENLHSKLIVSENSREGWGNLKELMKVFLCHPGWSTVARSWLTATSTSLVQAI--LSLL 244

  Fly   193 DGID-------HT---------LAILSSSGTSGFPKAVTISNSHKIIVDYMAINN--------SN 233
            ...|       ||         :||..:|||||:||..  :::|......:::|.        |:
Human   245 SSWDYRHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMT--AHTHSSFGLGLSVNGRFWLDLTPSD 307

  Fly   234 IQYTSSTLDWCSGLSMAITSGVFSTTSIIADC-------DFDPGLFCRAIGKYRISMVLLSSSYL 291
            :.:.:|...|    :.:..|.|||.. |...|       .|:|....:.:.||.|:
Human   308 VMWNTSDTGW----AKSAWSSVFSPW-IQGACVFTHHLPRFEPTSILQTLSKYPIT--------- 358

  Fly   292 AIFANCP---------EFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTEL--- 344
             :|.:.|         :..|....||.:.:..|...:.:|..|.|::...|... .||.||.
Human   359 -VFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYE-GYGQTETVLI 421

  Fly   345 --NSAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQGEAQEPNVVGEICFHNSQK-----WAGYYKN 402
              |..|     ...||.|:|:......:|::|..|....|...|:|.......     :..|..|
Human   422 CGNFKG-----MKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDN 481

  Fly   403 PDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACV 467
            |.:|...... |:..|||.||:|||||.:.:.|..|::........|.|:||.:.|.|:|.|:.|
Human   482 PSKTASTLRG-NFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAV 545

  Fly   468 FGIWDPVNGDEAAASLVKKPGTQLEAQ-----DVVEYVRKRITAKFK-QLNGGALIVDQI 521
            ....||:.|:...|.:|..|..:...|     ::.|:| |:.||.:| ....|.||:..|
Human   546 VSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHV-KKTTAPYKYPRKVGILIITNI 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	109/449 (24%)
		AFD_class_I	55..530	CDD:302604	109/449 (24%)
ACSM3	XP_024306135.1	AFD_class_I	54..596	CDD:327384	106/440 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920