Protein Alignment CG18586 and ACSM5

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001311301.1
• Gene: ACSM5 / 54988
• HGNCID: 26060
• Length: 582
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 90/374 - (24%)
• Similarity: 156/374 - (41%)
• Gaps: 68/374 - (18%)

  Fly   181 PVMQNFQPLRLKDGIDHT---------LAILSSSGTSGFPKAVTISNSH---KIIVD---YMAIN 230
            |...||:.|..:...:|.         |||..:|||:|.||.|..|.|.   ..:..   ::|:.
Human   198 PGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALT 262

  Fly   231 NSNIQYTSSTLDWCSG---LSMAITSGVFSTTSIIADCDF-------DPGLFCRAIGKYRISMVL 285
            .|:|.:.::...|...   |..|..:|         .|.|       |..:....:.|:.|:.:.
Human   263 ESDIFWNTTDTGWVKAAWTLFSAWPNG---------SCIFVHELPRVDAKVILNTLSKFPITTLC 318

  Fly   286 LSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTE-----LN 345
            ...:...:... .:.......||.:.:.||.:.:.:|:.|.:.:...: |...||.:|     .|
Human   319 CVPTIFRLLVQ-EDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVE-LYEGYGQSETVVICAN 381

  Fly   346 SAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQGEAQEPNVVGEI----------CFHNSQKWAGYY 400
            ..|     ...|..|:|:|.....::::|::|....|...|.:          ||.|.     |.
Human   382 PKG-----MKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNC-----YL 436

  Fly   401 KNPDETRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEA 465
            .||::|...:..:.:| |||...:|||||.:.:.|..|::...:....|.|:|:.:||.|.|||:
Human   437 DNPEKTAASEQGDFYI-TGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLES 500

  Fly   466 CVFGIWDPVNGDEAAASLVKKPG-----TQLEAQDVVEYVRKRITAKFK 509
            .|....||:.|:...|.:|..|.     .:...:::.|:| ||:||.:|
Human   501 AVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHV-KRVTAPYK 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	90/374 (24%)
		AFD_class_I	55..530	CDD:302604	90/374 (24%)
ACSM5	NP_001311301.1	Acs	49..552	CDD:223442	90/374 (24%)
		AFD_class_I	49..552	CDD:302604	90/374 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920