DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and Acsm4

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_859046.1	Gene:	Acsm4 / 353317	RGDID:	727928	Length:	580	Species:	Rattus norvegicus

Alignment Length:	554	Identity:	125/554 - (22%)
Similarity:	215/554 - (38%)	Gaps:	103/554 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DKLKIWSGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYM-R 82
            |.|..||.:|..              |:...||.|.......:::..:.::|...:.:.|:.: :
  Rat    57 DVLDQWSLKEKS--------------GERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTK 107

  Fly    83 NMGLGQTDIVGVMGRHTTHQSAVAYAC------FFNGT-------PLHALHNAYEEACIAKLFGI 134
            ..||.:.|.|.|:.........:..||      |..||       .|:.| .|.:..||.....:
  Rat   108 PCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRL-QASKAKCIVASEEV 171

  Fly   135 TKPRLIFCDGDEYEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLRLKDGIDHTL 199
            . |.:        :.:.|...:|:..::...:...|.:..|::|.:...::   ..::.|....:
  Rat   172 A-PAV--------DSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEH---NCVQTGSQEPM 224

  Fly   200 AILSSSGTSGFPKAVTISNSHKIIVDYMAINNSNIQYTSSTLDW---CSGLSMAITSGVFST--- 258
            ||..:|||:|.||....|.| .:.:.|.......:..|||.:.|   .:|...|....||||
  Rat   225 AIYFTSGTTGSPKMAQHSQS-SLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLR 288

  Fly   259 ---TSIIADCDFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSL 320
               ..:.....|:...|...:..|.|:.:..:.:...:... .:.:......|.:.:.||...:.
  Rat   289 GACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQ-QDLKRYQFKRLRHCLTGGEPLNP 352

  Fly   321 EV--QRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKPNSVGRAIRGIKIKVIDEQGEAQEPN 383
            ||  |.|.::.|.   |...||.||:....:.....:.||.|:|:.:....:::|||.|......
  Rat   353 EVLEQWKAQTGLE---LYEGYGQTEVGIICANRKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSG 414

  Fly   384 VVGEI----------CFHNSQKWAGYYKNPDETRQIQDS---ENWIHTGDLGYVDKDGYLFVIDR 435
            ..|||          ||     ::.|..||::|    |:   .|:..|||.|.:|.||||:.:.|
  Rat   415 KEGEIALRLGSDRPFCF-----FSEYVDNPEKT----DATIRRNFYITGDRGVMDDDGYLWFVGR 470

  Fly   436 LKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLV--------KKPGTQLE 492
            ..|::........|.|:|:.:.|.|.|:|:.|....||:.|:...|.:|        .:.....|
  Rat   471 ADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAE 535

  Fly   493 AQD-------------VVEYVR---KRITAKFKQ 510
            .||             .||:|:   |.||.|.|:
  Rat   536 LQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKR 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	120/538 (22%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	116/518 (22%)
Acsm4	NP_859046.1	MACS_euk	48..577	CDD:341251	125/554 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010