Protein Alignment CG18586 and hll

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 134/690 - (19%)
• Similarity: 236/690 - (34%)
• Gaps: 250/690 - (36%)

  Fly    20 KLKIWSGREAPSLFS---PNLSIGEII------FGDMVNNPKLIAQISITED---IVLTREDLHM 72
            ||::    :.||.||   |..:|.|..      :.|:   |.|:.:...:.:   ..||..:...
  Fly    20 KLRL----DEPSSFSQTVPPQTIPEFFKESCEKYSDL---PALVWETPGSGNDGWTTLTFGEYQE 77

  Fly    73 NAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPL-------------HALHNAYE 124
            ...:.|..:.::|:.:...||::..:........:.....|..:             |.|.....
  Fly    78 RVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGES 142

  Fly   125 EACI-------AKLFGITK--PRL-----------IFCDGD----EYEKVKSAT--KDLQVTIVT 163
            ..|:       |||..|.:  |||           .|.|.:    .::|::..|  .:|:..::.
  Fly   143 SVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKEELLA 207

  Fly   164 MRNHPRGSVRIQDVLTTPVMQNFQPLRLKDGIDHTLAILSSSGTSGFPKAVTISNSHKI------ 222
            ..:..|.                         :....::.:|||.|.||||.:|:.:.:
  Fly   208 RESRIRA-------------------------NECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSA 247

  Fly   223 -------------IVDYMAINNSNIQYTSSTLDWCSGLSMA--ITSGVFSTTSIIADCDFDPGLF 272
                         .|.|:.:::    ..:...|...|||.|  :|         .||.|...|..
  Fly   248 AAHMQDIQVGKESFVSYLPLSH----VAAQIFDVFLGLSHAGCVT---------FADKDALKGTL 299

  Fly   273 CRAIGKYR---------------------------ISMVLLSSSYLAIFANCPEFESADLSSLNY 310
            .:...|.|                           .|.:||:.:..|:    .|.::..::..:.
  Fly   300 IKTFRKARPTKMFGVPRVFEKLQERLVAAEAKARPYSRLLLARARAAV----AEHQTTLMAGKSP 360

  Fly   311 VIFGGSS--CSLEVQRKVRSRLSHD-------------------------CLNFCYGLTELNSAG 348
            .|:|.:.  .:..|.:.:|..:..|                         .|..|||::|  ::|
  Fly   361 SIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSE--TSG 423

  Fly   349 SVNLNFD-EKPNSVGRAIRGIKIKVIDEQGEAQEP--NVVGEICFHNSQKWAGYYKNPDETRQIQ 410
            ::.||.| ....|.|:|..|:.:|:       .||  |..|||.......:.||...||:|.:..
  Fly   424 AITLNVDISNLYSAGQACEGVTLKI-------HEPDCNGQGEILMRGRLVFMGYLGLPDKTEETV 481

  Fly   411 DSENWIHTGDLGYVDKDGYLFVIDRLKDML---KYQNIMYYPSEIENVI-AEMPNVLEACVFGIW 471
            ..:.|:|:|||||:|..|.|.:..|||:::   ..:||.  |..||.:| .|:|     ||..:.
  Fly   482 KEDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGENIP--PVHIEELIKKELP-----CVSNVL 539

  Fly   472 DPVNGDEAAASLV---------KKPGTQLEA--QDVVEYVRK----------------------- 502
              :.||......|         .|.|..|:|  ::.:|::|.
  Fly   540 --LIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIEWLRDLDIHETRLSELLNIPADLQLPND 602

  Fly   503 --------RITAKFKQLNGGALIVDQIVRSGNRKTNRSAV 534
                    .||||.|.|        :.:..|.::.|:.|:
  Fly   603 TAALAATLEITAKPKLL--------EAIEEGIKRANKYAI 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	128/672 (19%)
		AFD_class_I	55..530	CDD:302604	120/640 (19%)
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	122/641 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030