Protein Alignment CG18586 and ACSM2B

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001098539.1
• Gene: ACSM2B / 348158
• HGNCID: 30931
• Length: 577
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 126/538 - (23%)
• Similarity: 209/538 - (38%)
• Gaps: 85/538 - (15%)

  Fly    24 WSGREAPSLFSPNLSIGEII--FGDMVNNPKLIAQISI------TEDIVLTREDLHMNAMRVASY 80
            |..:|.|:.|:   ...:::  :.||....|.:...::      .::::....:|..|:.:.|:.
Human    35 WGHQEVPAKFN---FASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANI 96

  Fly    81 MRN-MGLGQTDIVGVMGRHTTHQSAVAYAC------FFNGT-------PLHALHNAYEEACIAKL 131
            :.. .||.:.|.|.||.........|...|      |..||       .|:.|..:..:|.:|
Human    97 LSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA-- 159

  Fly   132 FGITKPRLIFCDGD----EYEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQNFQPLRLK 192
                        ||    |.:.|.|....|::.::.......|.:..:.:|......:.   .::
Human   160 ------------GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHH---CVE 209

  Fly   193 DGIDHTLAILSSSGTSGFPKAVTISNSH-----KIIVDYMAINNSNIQYTSSTLDW----CSGLS 248
            .|.....||..:|||||.||....|.|.     |:...:..:..|:|.:|.|...|    ...|.
Human   210 TGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLL 274

  Fly   249 MAITSGVFSTTSIIADCDFDPGLFCRAIGKYRI-SMVLLSSSYLAIFANCPEFESADLSS----- 307
            .:.|.|..:...::.  .|||.:..:.:..|.| ||:.....|..:.       ..||||
Human   275 ESWTLGACTFVHLLP--KFDPLVILKTLSSYPIKSMMGAPIVYRMLL-------QQDLSSYKFPH 330

  Fly   308 LNYVIFGGSSCSLEVQRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKPNSVGRAIRGIKIKV 372
            |...:.||.|...|.....|::...|...| ||.||......|:.....||..:|.|.....::|
Human   331 LQNCLAGGESLLPETLENWRAQTGLDIREF-YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394

  Fly   373 IDEQGEAQEPNVVGEICFHNSQ-----KWAGYYKNPDETRQIQDSENWIHTGDLGYVDKDGYLFV 432
            ||::|....|...|:|......     .::||.:|||:|......:.|: .||.|..|:|||...
Human   395 IDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQF 458

  Fly   433 IDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLVKKPGTQLEAQDVV 497
            :.|..|::........|||:||.:.:.|.|:|..|....|||.|:...|.::.  .:|..:.|..
Human   459 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL--ASQFLSHDPE 521

  Fly   498 EYVR------KRITAKFK 509
            :..:      |.:||.:|
Human   522 QLTKELQQHVKSVTAPYK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	122/527 (23%)
		AFD_class_I	55..530	CDD:302604	119/505 (24%)
ACSM2B	NP_001098539.1	AFD_class_I	40..568	CDD:388389	124/533 (23%)
		Coenzyme A binding. /evidence=ECO:0000250	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000250	540..542		126/538 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920