Protein Alignment CG18586 and ACSM4

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001073923.1
• Gene: ACSM4 / 341392
• HGNCID: 32016
• Length: 580
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 125/568 - (22%)
• Similarity: 209/568 - (36%)
• Gaps: 131/568 - (23%)

  Fly    19 DKLKIWSGREAPSLFSPNLSIGEIIFGDMVNNPKLIAQISITEDIVLTREDLHMNAMRVASYM-R 82
            |.|..||.:|..              |:...||.|.......:::..:..:|...:.:.|:.: :
Human    57 DVLDQWSQKEKT--------------GERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTK 107

  Fly    83 NMGLGQTDIVGVMGRHTTHQSAVAYAC------FFNGT-------PLHALHNAYEEACIAKLFGI 134
            ..||.:.|.:.|:.........|..||      |..||       .|:.|..:..:..:|.
Human   108 PCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVAS---- 168

  Fly   135 TKPRLIFCDGDEYEKVKSATKDLQVTIVTMRNHPRGSVRIQDVLTTPVMQN----FQPL------ 189
                         |:|..|.:.:.:....::.         .:|.:|...|    ||.|
Human   169 -------------EEVAPAVESIVLECPDLKT---------KLLVSPQSWNGWLSFQELFQFASE 211

  Fly   190 ---RLKDGIDHTLAILSSSGTSGFPKAVTISNSHKII------VDYMAINNSNIQYTSSTLDWCS 245
               .::.|....:.|..:|||:||||....|.|...|      ..::.:.:|:|.:..|...|..
Human   212 EHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVK 276

  Fly   246 GLSMAITSGVFSTTSIIADC-------DFDPGLFCRAIGKYRISMVLLSSSYLAIFANCPEFESA 303
                |....|||:. :...|       .||...|...:..|.|:.:....:...:... .:.:..
Human   277 ----AAIGSVFSSW-LCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQ-KDLKRY 335

  Fly   304 DLSSLNYVIFGGSSCSLEV--QRKVRSRLSHDCLNFCYGLTELNSAGSVNLNFDEKPNSVGRAIR 366
            ...||.:.:.||...:.||  |.:|::.|.   |...||.||:....:.....:.||.|:|:.:.
Human   336 KFKSLRHCLTGGEPLNPEVLEQWRVQTGLE---LYEGYGQTEVGMICANQKGQEIKPGSMGKGML 397

  Fly   367 GIKIKVIDEQGEAQEPNVVGEI----------CFHNSQKWAGYYKNPDETRQIQDSENWIHTGDL 421
            ...:::|||.|....|...|||          ||     ::.|..||.:|......:.:: |||.
Human   398 PYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCF-----FSKYVDNPQKTAATIRGDFYV-TGDR 456

  Fly   422 GYVDKDGYLFVIDRLKDMLKYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDEAAASLV-- 484
            |.:|.|||.:.:.|..|::........|.|:|:.:.|.|.|:|:.|....|.:.|:...|.:|
Human   457 GVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLA 521

  Fly   485 ------KKPGTQLEAQD-------------VVEYVR---KRITAKFKQ 510
                  ......||.||             .||:|:   |.||.|.|:
Human   522 APFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	120/552 (22%)
		AFD_class_I	55..530	CDD:302604	116/532 (22%)
ACSM4	NP_001073923.1	MACS_euk	48..577	CDD:213294	125/568 (22%)
		Acs	49..580	CDD:223442	125/568 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920