Protein Alignment CG18586 and SLC27A6

DIOPT Version :9

• Sequence 1: NP_647993.2
• Gene: CG18586 / 38659
• FlyBaseID: FBgn0035642
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001017372.1
• Gene: SLC27A6 / 28965
• HGNCID: 11000
• Length: 619
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 116/572 - (20%)
• Similarity: 216/572 - (37%)
• Gaps: 138/572 - (24%)

  Fly    59 ITEDIVLTREDLHMNAMRVAS-YMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGTPLHALHNA 122
            |.|..:.|.:|:...:.|||. ::.:..|.:.|.|.::..:......|.:.....|..:..|:..
Human    74 IYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138

  Fly   123 YEEACIAKLFGITKPRLIFCDGDEYEKVKSATKDL--QVTIVTMRNH-PRGSVRIQDVLTT---- 180
            .....:........||.:....|....|:.....|  .:::..|::. |:|.:.:::.|:|
Human   139 IRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDE 203

  Fly   181 PVMQNFQPLRLKDGIDHTLAILSSSGTSGFPKAVTIS----------------NSHKIIVDYMAI 229
            ||.::...:.|   :..|...:.:|||:|.|||..||                .:|.|:  |:.:
Human   204 PVPRSHHVVSL---LKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIV--YITL 263

  Fly   230 NNSNIQYTSSTLDWCSGLSMAITSGV-------FSTTSIIADC-DFDPGLF------CRAIGKYR 280
               .:.::|:.:   .|:|..:..|.       ||.:...:|| .:|..:|      ||
Human   264 ---PLYHSSAAI---LGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCR------ 316

  Fly   281 ISMVLLSSSYLAIFANCPEFESADLSSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFC--YGLTE 343
                     ||     |.:.:..........:..|:....:|.|:...|..:  :..|  |..||
Human   317 ---------YL-----CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGN--IKVCELYAATE 365

  Fly   344 LNSAGSVN-LNFDEKPNSVGRAIRGIKI----KVIDEQGEAQEPNVVGEICFHNSQKW------- 396
                .|:: :|:..:..::||.....|:    .:|....:..||       ..|.|.|
Human   366 ----SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEP-------MRNEQGWCIHVKKG 419

  Fly   397 ------------------AGYYKNPDE---TRQIQDSENWIHTGDLGYVDKDGYLFVIDRLKDML 440
                              ||.||:..:   ....:..:.:::||||...|:|.:|:..||..|..
Human   420 EPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484

  Fly   441 KYQNIMYYPSEIENVIAEMPNVLEACVFGIWDPVNGDE---AAASLVKKPGTQLEAQDVVEYVRK 502
            :::......:|:.:||..:..:.||.|:|:  .::|.|   ..||::.||.|.|:.:.|.|.|..
Human   485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAGMASIILKPNTSLDLEKVYEQVVT 547

  Fly   503 -----------RITAKFKQLNGGALIVDQIVRSGNRKTNRSAVKE--HFLKN 541
                       ||..|.:......|:..|:|..|   .|...:.|  :|:.|
Human   548 FLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDG---FNPLKISEPLYFMDN 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	115/570 (20%)
		AFD_class_I	55..530	CDD:302604	112/557 (20%)
SLC27A6	NP_001017372.1	PRK08279	16..619	CDD:236217	116/572 (20%)
		hsFATP2a_ACSVL_like	77..609	CDD:213304	114/569 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149148
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840