DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18586 and Acsl3

DIOPT Version :9

Sequence 1:	NP_647993.2	Gene:	CG18586 / 38659	FlyBaseID:	FBgn0035642	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_476448.1	Gene:	Acsl3 / 114024	RGDID:	70552	Length:	720	Species:	Rattus norvegicus

Alignment Length:	525	Identity:	114/525 - (21%)
Similarity:	191/525 - (36%)	Gaps:	137/525 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NPKLIAQISITEDIVLTREDLHMNAMRVASYMRNMGLGQTDIVGVMGRHTTHQSAVAYACFFNGT 114
            |.|:..::.:.....|:.||:.:.|:...:.::.:|......:.:...........|.|||....
  Rat   120 NGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNF 184

  Fly   115 PLHALHNAYEEACIAKLFGITKPRLIFCDGDEYEKVKSATKDLQVTIVTMRNH------------ 167
            .|..|:.......|......|:...|.   ...|.:::..||: |::|....|
  Rat   185 QLVTLYATLGGPAIVHGLNETEVTNII---TSKELLQTKLKDI-VSLVPRLRHIITVDGKPPTWS 245

  Fly   168 --PRGSVRIQDVLTTPVMQNFQPLRLKDGID---HT-------LAILSSSGTSGFPKAVTISNSH 220
              |:|.:       ...|...|.|.:|..:|   |:       ..|:.:||::|.||.|.||:|:
  Rat   246 EFPKGVI-------VHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSN 303

  Fly   221 ------------------KIIVDYMAI--------------NNSNIQYTS-STLDWCSGLSMAIT 252
                              .:.:.|:.:              :...|.|:| .||   :..|..|.
  Rat   304 IIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTL---ADQSSKIK 365

  Fly   253 SGVFSTTSIIAD------------------------CDFDPGLFCRAIGKYRISMVLLS---SSY 290
            .|....||::..                        ..|...||..|   |...|..:|   |:.
  Rat   366 KGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILA---YNYKMEQISKGCSTP 427

  Fly   291 LAIFANCPEFESADL-----SSLNYVIFGGSSCSLEVQRKVRSRLSHDCLNFC--------YGLT 342
            |     |..|...::     .::..::.||:..|...||         .:|.|        ||||
  Rat   428 L-----CDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQR---------FMNICFCCPVGQGYGLT 478

  Fly   343 ELNSAGSVNLNFDEKPNSVGRAI--RGIKIKVIDEQG--EAQEPNVVGEICFHNSQKWAGYYKNP 403
            |...||::...:|.....||..:  ..||:|..:|.|  ...:|:..|||.........|||||.
  Rat   479 ESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNE 543

  Fly   404 DETR----QIQDSENWIHTGDLGYVDKDGYLFVIDRLKDMLKYQNIMYYP-SEIENVIAEMPNVL 463
            .:|:    :.::.:.|:.|||:|..|.||.|.:|||.||::|.|...|.. .::|..:..:|.:.
  Rat   544 AKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLID 608

  Fly   464 EACVF 468
            ..|.:
  Rat   609 NICAY 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18586	NP_647993.2	CaiC	35..541	CDD:223395	114/525 (22%)
CG18586	NP_647993.2	AFD_class_I	55..530	CDD:302604	112/520 (22%)
Acsl3	NP_476448.1	PLN02387	30..717	CDD:215217	114/525 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930