DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5568 and 4CL8

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_198628.2	Gene:	4CL8 / 833792	AraportID:	AT5G38120	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	145/563 - (25%)
Similarity:	247/563 - (43%)	Gaps:	56/563 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGELQAGKSPFKTRNTF-DENLKIWSGGEKRSLFSPD-LSIGEIIFQQMERNAMLTAQISVTENT 63
            |...|...|....||.| ..|...:|..:..:|.|.: |.|...|..|..|..  ||.|....:.
plant     1 MANSQRSSSLIDPRNGFCTSNSTFYSKRKPLALPSKESLDITTFISSQTYRGK--TAFIDAATDH 63

  Fly    64 ELTWKDIQTNAMKVAS-YMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNG---TPYHALHTEYE 124
            .:::.|:.....:||. .:..:|:.:||.|.|:...|..:..:..:....|   |..:.|:|
plant    64 RISFSDLWMAVDRVADCLLHDVGIRRGDVVLVLSPNTISIPIVCLSVMSLGAVLTTANPLNT--- 125

  Fly   125 QSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNHPAGILRIQDILTTP-------- 181
            .|.|.|....:.|:|.|...:...|:  |:.|:.:.:.          |::|.|..|
plant   126 ASEILRQIADSNPKLAFTTPELAPKI--ASSGISIVLE----------RVEDTLRVPRGLKVVGN 178

  Fly   182 ------VEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISN-------SHQIIGSFLPVDSSI 233
                  .|.:.:.||.:...|....:|.||||:|..|.|..|:       :..|...|.....:.
plant   179 LTEMMKKEPSGQAVRNQVHKDDTAMLLYSSGTTGRSKGVNSSHGNLIAHVARYIAEPFEQPQQTF 243

  Fly   234 IQYNPNTLDWASGITMTINAAVFSLTSIIEDCDFDPANLCGLIEKYR-ISMVFVSSSQLAMLSNC 297
            |...|  |....|:...:.|.:...|:::....||...:...:|||| .:::.|....:.|::..
plant   244 ICTVP--LFHTFGLLNFVLATLALGTTVVILPRFDLGEMMAAVEKYRATTLILVPPVLVTMINKA 306

  Fly   298 PEFYAA-DLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDE--KPN 359
            .:.... |:|.::....||:..|.||......:.....|...|.|||.|..|....:.:|  :..
plant   307 DQIMKKYDVSFLRTVRCGGAPLSKEVTQGFMKKYPTVDVYQGYALTESNGAGASIESVEESRRYG 371

  Fly   360 SVGRPVRGIQIKIVN-ELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGY 423
            :||....|::.:||: ..|:..|.|..||:.........||::|.||   :..||.|..||||.|
plant   372 AVGLLSCGVEARIVDPNTGQVMGLNQTGELWLKGPSIAKGYFRNEEE---IITSEGWLKTGDLCY 433

  Fly   424 MDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQG 488
            :|.||:|||:||||:::||:.....|:|:|:::...|::::|.|....|...|....|.|.:|..
plant   434 IDNDGFLFIVDRLKELIKYKGYQVPPAELEALLLNHPDILDAAVIPFPDKEAGQFPMAYVARKPE 498

  Fly   489 TQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHIIQSGNRKANR 531
            :.|..:.|::::.|:: |.:|::...|.| |.|.::.:.|..|
plant   499 SNLCEKKVIDFISKQV-APYKKIRKVAFI-DSIPKTPSGKTLR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	135/528 (26%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	128/504 (25%)
4CL8	NP_198628.2	PLN02574	17..542	CDD:215312	140/547 (26%)
4CL8	NP_198628.2	4CL	33..542	CDD:213272	137/531 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920