Protein Alignment CG5568 and ACSF2

DIOPT Version :9

• Sequence 1: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 581
• Identity: 139/581 - (23%)
• Similarity: 244/581 - (41%)
• Gaps: 93/581 - (16%)

  Fly     2 GELQAGKSPFKTRNTFDENLKIWSGGEKRSLFSP----------------DLSIGEIIFQQMERN 50
            |.::||:......::|..:....|....|.:.:|                ..::|:.:....:|.
Human    46 GGMEAGRQRISVPSSFTASAAAHSREVDRMVSTPIGGLSYVQGCTKKHLNSKTVGQCLETTAQRV 110

  Fly    51 AMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGR------LTTHLTALAYAC 109
            ....|.:.:.|:..||:..::....|.||.:..:||.:||.:|:.|.      |....||.|...
Human   111 PEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGII 175

  Fly   110 FFNGTP-YHALHTEYEQSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNHPAGILR 173
            ..:..| |.|:..||.      |..:....|:|  ..:| |.|.....|:.....:.|...|.|:
Human   176 LVSVNPAYQAMELEYV------LKKVGCKALVF--PKQF-KTQQYYNVLKQICPEVENAQPGALK 231

  Fly   174 IQDI--LTTPVEMNFRPVRLKDGT----------------DQL------------LAILSSSGTS 208
            .|.:  |||.:.:: .|:   .||                |||            :.|..:|||:
Human   232 SQRLPDLTTVISVD-APL---PGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTT 292

  Fly   209 GLPKAVTIS-----NSHQIIGSFL------PVDSSIIQYNP--NTLDWASGITMTINAAVFSLTS 260
            |.||..|:|     |:..|:|..|      |....:|..||  :.|...:|..|.:   ::..|.
Human   293 GSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCL---MYGATL 354

  Fly   261 IIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNCSLEVQNK 325
            |:....|:.......|.:.|.:.::.:.:....:.|.|:|.:.|:|::......||....|:...
Human   355 ILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIRA 419

  Fly   326 IRSRLSNECVNFSYTLTELNSPGCLNF------NFDEKPNSVGRPVRGIQIKIVN-ELGEAQGPN 383
            |.::::.:.:..:|..|| |||  :.|      ..::|..||||.:...:.:|:| |.|.....|
Human   420 IINKINMKDLVVAYGTTE-NSP--VTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLN 481

  Fly   384 VVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYY 448
            ..||:|........||:..|::|::..|.:.|:.|||:..|:|.|:..|:.|.|||:.......|
Human   482 TPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIY 546

  Fly   449 PSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFK 509
            |:|:|......|.|.|..|.|:.|...|::..|.:..|.|.:...:::..:.:.:| :.||
Human   547 PAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKI-SHFK 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	133/548 (24%)
		Firefly_Luc_like	55..530	CDD:213279	130/512 (25%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	132/545 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810