DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and Acsf2

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001030123.1	Gene:	Acsf2 / 619561	RGDID:	1562656	Length:	615	Species:	Rattus norvegicus

Alignment Length:	516	Identity:	128/516 - (24%)
Similarity:	227/516 - (43%)	Gaps:	51/516 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGR----- 97
            ::||.:....:|.....|.:.:.||..|.:..::....:.||.:..:||.:||.:|:.|.
  Rat    73 TVGECLDATAQRFPNREALVIIHENIRLNFAQLKEEVDRAASGLLSIGLRKGDRLGMWGPNSYAW 137

  Fly    98 -LTTHLTALAYACFFNGTP-YHALHTEY-------------EQSAIERLFGITKPRLIFCDGDEF 147
             |....||.|.....:..| |.|...||             :|...::.:.|.|.   .|  .|.
  Rat   138 VLIQLATAQAGIILVSVNPAYQASELEYVLRKVGCKGIVFPKQFKTQQYYNILKQ---VC--PEL 197

  Fly   148 EKVQ-AATKGLQV----QIVTMRNHPAGILRIQDILTT-PVEMNFRPVRLKDG---TDQLLAILS 203
            ||.| .|.|..::    .::::.....|.|.:.:::.. ..|.|...:|...|   ....:.|..
  Rat   198 EKAQPGALKSERLPDLTTVISVDAPLPGTLLLDEVVAAGGKEQNLAQLRYHQGFLSCYDPINIQF 262

  Fly   204 SSGTSGLPKAVTIS-----NSHQIIGSFLPVDSSIIQ----YNPNTLDWASG-ITMTINAAVFSL 258
            :|||:|.||..|:|     |:..:||..|.:.:...:    ..|..|....| :..|:.:.|...
  Rat   263 TSGTTGNPKGATLSHHNIVNNSNLIGQRLKMPAKTAEELRMVLPCPLYHCLGSVGGTMVSVVHGA 327

  Fly   259 TSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNCSLEVQ 323
            |.::....|:.......|.:.:.::::.:.:....:.|.|:|.:.|.::::.....||....|:.
  Rat   328 TLLLSSPSFNGKKALEAISREKGTLLYGTPTMFVDILNQPDFSSYDFTTIRGGVIAGSLAPPELI 392

  Fly   324 NKIRSRLSNECVNFSYTLTELNSP-GCLNF---NFDEKPNSVGRPVRGIQIKIVN-ELGEAQGPN 383
            ..|.|:::.:.:...|..|| ||| ..:||   ..::|..||||.:...:.:||| |.||....|
  Rat   393 RAIISKMNMKELVVVYGTTE-NSPVTFMNFPEDTLEQKAGSVGRIMPHTEAQIVNMETGELTKLN 456

  Fly   384 VVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYY 448
            :.||:|........||:..|::|.:....:.|:.|||:..|||.|:..|:.|.|||:.......|
  Rat   457 MPGELCIRGYCVMQGYWGEPQKTFETVGQDRWYRTGDIASMDEQGFCRIVGRSKDMIIRGGENIY 521

  Fly   449 PSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFK 509
            |:|:|....:.|.|.||.|.|:.|...|::..|.:..|.|.....:::..:.:.:| :.||
  Rat   522 PAELEDFFHKHPQVQEAQVVGVKDDRMGEEICACIRLKSGETTTEEEIKAFCKGKI-SHFK 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	128/516 (25%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	125/499 (25%)
Acsf2	NP_001030123.1	PRK08315	57..615	CDD:236236	128/516 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810