DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and slc27a1b

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001070716.1	Gene:	slc27a1b / 553512	ZFINID:	ZDB-GENE-061013-672	Length:	648	Species:	Danio rerio

Alignment Length:	521	Identity:	123/521 - (23%)
Similarity:	200/521 - (38%)	Gaps:	111/521 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VTENTELTWK----DIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHAL 119
            |.|::...|.    |.::||  ||.::...|...||.|.:.......:.||.......|.
Zfish    98 VDESSGEVWSFSELDRRSNA--VAQWVLAQGWRSGDVVAIFMESRPQMVALWLGMAKVGV----- 155

  Fly   120 HTEYEQSAIERLFGITKPRLIFCDG--------------DEFEKVQAATKGLQVQIVTMRNHPAG 170
                |.:.|.  |.:.:..||.|.|              |...:|:.:.:.|  .:.:..:.||.
Zfish   156 ----EPALIN--FNLRRDSLIHCMGVSGACGMVFGAELLDVVLEVRESLRSL--SLFSCGSAPAE 212

  Fly   171 IL------RIQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSH--------- 220
            :|      .:..:|:...|........|...|:|..|. :|||:|||||..:.:|.
Zfish   213 MLDSLSAADLDALLSKSPETPPAVAHNKGFNDRLFYIY-TSGTTGLPKAAIVVHSRYYRIAAFSY 276

  Fly   221 --------QIIGSFLPVDSS---IIQYNPNTLDWASGITMTINAAVFSLTSIIEDC---DFDPAN 271
                    .::...||:..|   ||......|   .|:|:.|... ||.:...:||   :.....
Zfish   277 YSFGLQPDDVVYCCLPLYHSAGNIIGVGQCLL---HGLTVVIRRK-FSASRFWDDCVKYNCTVVQ 337

  Fly   272 LCGLIEKYRISMVFVSSSQL-----AMLSNC-PEFYAADLS--SVKYF--FYGGS--NCSL-EVQ 323
            ..|.|.:|.:|.....|..|     ||.:.. |..:.:.:.  |||..  |||.:  |||| .:.
Zfish   338 YIGEICRYLLSQPVRPSESLHRVRVAMGNGLRPNVWESFMKRFSVKRIGEFYGATECNCSLANMD 402

  Fly   324 NKIRSRLSNECVNFS-YTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVNELGEAQGPN-VVG 386
            ||:.:...|..|..| |.:..|.:        ||....:.|..||:.:..  :.||   |. :||
Zfish   403 NKVGACGFNSVVLPSVYPIRLLRA--------DEDTMELIRDSRGLCVPC--KPGE---PGIIVG 454

  Fly   387 EICFNNGQ----KWPGYYKNPEETKKMQDSENWFHTGDLGY-------MDEDGYLFIIDRLKDML 440
            .|   |.|    ::.||......:||:  |.|.|..||..|       |||.||::..||..|..
Zfish   455 RI---NPQDPLRRFDGYANEEATSKKI--SHNVFRKGDSAYVSGDLMVMDELGYVYFRDRGGDTF 514

  Fly   441 KYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIP 505
            :::......:|:|.|::.:....:..|:|:..|....||..:.:.......:.:..:..|:..:|
Zfish   515 RWRGENVSTTEVEGVLSALLKQTDVAVYGVSVPGVEGKAGMAAIADPENVFDCETFLRDVQNALP 579

  Fly   506 A 506
            :
Zfish   580 S 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	123/521 (24%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	123/521 (24%)
slc27a1b	NP_001070716.1	PRK08279	60..648	CDD:236217	123/521 (24%)
slc27a1b	NP_001070716.1	AFD_class_I	103..613	CDD:302604	121/516 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930