Protein Alignment CG5568 and SLC27A1

DIOPT Version :9

• Sequence 1: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 122/567 - (21%)
• Similarity: 197/567 - (34%)
• Gaps: 171/567 - (30%)

  Fly    42 IIFQQMERNAMLTAQISVTENTELTWKDIQTNAMK--VASYMRKLGLEQGDFVGVIGRLTTHLTA 104
            ::.:|.||.|::.|      .|...|...|.:|..  ||:..|:||...||.|
Human    85 VVQRQPERLALVDA------GTGECWTFAQLDAYSNAVANLFRQLGFAPGDVV------------ 131

  Fly   105 LAYACFFNGTP-YHALHTEYEQSAIERLF---GITKPRLIFCDGDEFEKVQAATKGLQVQIVTMR 165
               |.|..|.| :..|.....::.:|...   .:.:..|.||.|....|.......:...:..:.
Human   132 ---AIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVS 193

  Fly   166 NH--------------PAGILRIQDILTTPV--EMNFRPVRL--KDGTDQLLAILSSSGTSGLPK 212
            .|              |.|||....:| .|:  |.:..|:..  ..|.|..|..:.:|||:||||
Human   194 GHLGKSLIKFCSGDLGPEGILPDTHLL-DPLLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPK 257

  Fly   213 AVTISNS---------------------------HQIIGSFLPVDSSIIQYNPNTLDWASGITMT 250
            |..:.:|                           :...|:.:.|...:|.          |:|:.
Human   258 AAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIY----------GLTVV 312

  Fly   251 INAAVFSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGG 315
            :... ||.:...:||           .||..::..|...:|..|            .|:|.   |
Human   313 LRKK-FSASRFWDDC-----------IKYNCTINGVRHCRLLCL------------VVQYI---G 350

  Fly   316 SNC-----------------SLEVQNKIRSRLSNEC--------VNFSYTLTELNSPGCLNFNFD 355
            ..|                 .|.|.|.:|..:..|.        :...|..||.|   |...|.|
Human   351 EICRYLLKQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECN---CSIANMD 412

  Fly   356 EKPNSVG---------RPVRGIQIKIVNE-----LGEAQG---PNVVGEICFNNGQ--------K 395
            .|..|.|         .|:|.::   |||     |.:|||   |...||.....||        :
Human   413 GKVGSCGFNSRILPHVYPIRLVK---VNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRR 474

  Fly   396 WPGYYKNPEETKKMQDS-----ENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESV 455
            :.||......:||:..|     ::.:.:||:..|||.||::..||..|..:::......:|:|.|
Human   475 FDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGV 539

  Fly   456 IAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRK 502
            ::.:....:..|:|:..|....||..:.|....:.|:...:.:.::|
Human   540 LSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQK 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	122/567 (22%)
		Firefly_Luc_like	55..530	CDD:213279	118/554 (21%)
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	122/567 (22%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	18/70 (26%)
		AFD_class_I	101..623	CDD:302604	116/545 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930