DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and Acsm5

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001014184.3	Gene:	Acsm5 / 361637	RGDID:	1309578	Length:	578	Species:	Rattus norvegicus

Alignment Length:	553	Identity:	126/553 - (22%)
Similarity:	218/553 - (39%)	Gaps:	93/553 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LQAGKSPFKTRNTFDEN-LKIWSGGEKRSLFSPDLSIGEIIFQQMERNAMLTAQISVTENTELTW 67
            :..||.|......|..: |.:||..||.....|:.:...:       |.         ..||:.|
  Rat    41 ISLGKRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWV-------NG---------SGTEVKW 89

  Fly    68 --KDIQTNAMKVASYMR-KLGLEQGD-FVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSAI 128
              :::...:.|.|:.:. ..||:.|| .:.|:.||......:. ||...|.......::..|..:
  Rat    90 TFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIV-ACMRTGVVMIPGISQLTQKDL 153

  Fly   129 E-RLFGITKPRLIFCD--GDEFEKVQAATKGLQVQIVTMRNHPAGILRIQDIL--TTPVEMNFRP 188
            : ||.......:|..|  ....:.:.|....||.:::.......|.:..:::|  .:| |.|...
  Rat   154 KYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASP-EHNCLR 217

  Fly   189 VRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIG------SFLPVDSSIIQYNPNTLD----- 242
            .|..|.    :||..:|||:|.||.|..|.....:|      ..:.:..|.|.:  ||.|
  Rat   218 TRSGDS----MAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFW--NTTDTGWVK 276

  Fly   243 --------WASGITMTIN--AAVFSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNC 297
                    ||:|..:.::  ..|.:.|.:...|.|....:|.:...:|:   .|..........|
  Rat   277 AAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRL---LVQEDLTRYKFQC 338

  Fly   298 PEFYAADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDE-KPNSV 361
                      :::...||...:.:|::|.:::...| ::..|..:| ....|.||.... |..|:
  Rat   339 ----------LRHCLAGGEALNSDVRDKWKNQTGLE-IHEGYGQSE-TVLICGNFRGSTIKSGSM 391

  Fly   362 GRPVRGIQIKIVNELGEAQGPNVVGEI----------CFNNGQKWPGYYKNPEETKKMQDSENWF 416
            |:......::||:|.|....|...|.|          |..|     .|..|||:|...:..: ::
  Rat   392 GKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFN-----CYLDNPEKTAASEQGD-FY 450

  Fly   417 HTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAA 481
            .|||..:||||||.:.:.|..|::...:....|.|:||.:||.|.|:|:.|....||:.|:...|
  Rat   451 ITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 515

  Fly   482 SVV-----KKQGTQLEAQDVVEYVRKRIPAKFK 509
            .:|     .....:...:::.|:| |.:.|.:|
  Rat   516 FIVLSPAYVSHDPEALTRELQEHV-KTVTAPYK 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	117/521 (22%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	115/501 (23%)
Acsm5	NP_001014184.3	AFD_class_I	48..576	CDD:418409	123/546 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010