DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5568 and acsbg2

DIOPT Version :9

Sequence 1:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001119851.1	Gene:	acsbg2 / 335159	ZFINID:	ZDB-GENE-030131-7099	Length:	752	Species:	Danio rerio

Alignment Length:	716	Identity:	155/716 - (21%)
Similarity:	238/716 - (33%)	Gaps:	280/716 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KTRNTFDENLKIWSGGEKRSLFSPD-LSI-------------GEIIFQQMERNAMLTAQISVTEN 62
            :|....:::....||...|    || ||:             ||:..:..|..  |.|:..:|.|
Zfish    62 QTNTKAEQSTHTTSGATPR----PDSLSLPTKGTELWTTHRDGEVKLRMAESG--LGAETPLTVN 120

  Fly    63 TELT-------------WKD-IQTNAMKVASYMR----------KLGLEQGDFVGVIGRLTTHLT 103
            ...|             ||: .|...|..:.|.:          |||||:...||::|
Zfish   121 QMFTSTVQRFGSYPALGWKEGEQWKTMTYSEYYKSCRTAAKSFLKLGLERYHGVGILG------- 178

  Fly   104 ALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDG--------DEFEKVQAATKGLQVQ 160
                   ||.|.:.                |.....|...|        :..|..|...:..|..
Zfish   179 -------FNSTEWF----------------IADIAAILAGGFAVGIYTTNSPEACQYVAENCQAN 220

  Fly   161 IVTMRNHP--AGILRIQD-------ILTTPVEMNFRPVRL----------KDGTD-QLLAILSS- 204
            |:.:.||.  ..||:|||       |:....|:..:...|          :|..| ||..|:||
Zfish   221 ILVVENHKQLQKILQIQDKLPHLKAIIQYKDELKEKKPNLYTWAEFMELGRDEPDTQLDDIISSQ 285

  Fly   205 -----------SGTSGLPKAVTISN--------------------------------SH---QII 223
                       |||:|.||.|.:|:                                ||   |:|
Zfish   286 KPNQCCTLIYTSGTTGQPKGVMLSHDNLTWTAVATSQHVSLNDADKLQEVVVSYLPLSHIAAQMI 350

  Fly   224 GSFLPVDSSIIQY--NP--------NTL------------------------------------- 241
            ..:||:.:..:.|  .|        |||
Zfish   351 DIWLPMKAGGVTYFAQPDALKGSLANTLREIRPTAFLGVPRVWEKMQEKMKSIGAKSSTVRRKVA 415

  Fly   242 DWASGITMTINAAVFSLTSIIEDCDFDPANLCGLIEKYRIS--MVFVSSSQLAMLSNCPEFY--A 302
            .||..:.:..|.....|.|...    .|.|       ||::  :||....:...|..|...|  |
Zfish   416 SWAKDVGLQTNLNKMELGSNSR----KPLN-------YRLAKHLVFRKVRKALGLDRCTRCYTGA 469

  Fly   303 ADLS--SVKYF---------FYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDE 356
            |.::  ::::|         .||.|..|                 ..:|:|:.|:     |..
Zfish   470 APITKDTLEFFLSLDIPLFELYGMSESS-----------------GPHTITQANA-----FRL-- 510

  Fly   357 KPNSVGRPVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDL 421
              .|.|:.:.|.:.|:.|...|..     |||||.....:.||...|::|::..|:|.|.|:|||
Zfish   511 --TSCGKVIPGCKTKLSNPDDEKN-----GEICFWGRHVFMGYLNMPDKTEEALDAEGWLHSGDL 568

  Fly   422 GYMDEDGYLFIIDRLKDML---KYQTIMYYPSEIESVIAE-MPNVVEACVFGIWDPVYGDKAA-A 481
            |.:||:.:|||..|:|:::   ..:.|.  |..||..:.| :|.:..|.:.       |||.. .
Zfish   569 GKLDENNFLFITGRIKELIITAGGENIP--PVPIEDAVKEAIPLISNAMLI-------GDKRKFL 624

  Fly   482 SVVKKQGTQLEAQ----------DVVEYVRK--RIPAKFKQLNGGA-LIVDHIIQSGNRKANRAA 533
            |::.....|:..:          :.||:.||  ....:..::.||. ..|...||.|..:.|..|
Zfish   625 SMLLTVKCQINGETGVPEDELTPEAVEFCRKLGSSCTRVTEIAGGRDRAVQAAIQDGINRVNEKA 689

  Fly   534 T 534
            |
Zfish   690 T 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	151/693 (22%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	140/653 (21%)
acsbg2	NP_001119851.1	FAA1	118..738	CDD:223953	142/654 (22%)
acsbg2	NP_001119851.1	ACSBG_like	139..736	CDD:213299	138/633 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930